BIOCOMPATIBILITIES AND CHARACTERIZATION TECHNIQUES

BENG453

Course Code: BENG453
Semester: -
Theory+Practice: 3 + 1
ECTS: 5

Course Type

Elective Course

Course Level

Bachelor's Degree

Year of Study

Semester

ECTS

Name of Lecturer(s)

Learning Outcomes

At the end of this course, the students;

Learn material bulk structure characterizations and describe the range of tests
Select appropriate test methods depend on cases
Understand fundamental concepts related to biocompability, biological performance of materials used in medical devices and biomaterials
Learn biological performance testing strategy and certifications
Capable of presentation written report

Mode of Delivery

Face to face

Prerequisites

Recommended Optional Programme Components

None

Course Description

This course has two parts. In the first part, it will focus on material bulk structure characterizations such as IR, Raman Spectroscopy, Xray diffractions, Polarisation techniques, refractometry and conductivity measurement (DC or AC). In the second part, it will focus on biocompability tests and encourage student learning in the field of biocompatibility, with emphasis on understanding biological responses to the broad range of invasive medical devices and materials available.

Course Contents

WEEK	TOPICS
1^st Week	Material Characterizations
2^nd Week	Morphology, micro and nanodimensions, multiphases, nanoparticles
3^rd Week	Structural Characterizations (IR, Raman Spectroscopy)
4^th Week	Structural Characterizations (Xray diffractions)
5^th Week	Polarization techniques
6^th Week	Refractometry and nanomaterial characterization
7^th Week	Conductivity measurement (AC and DC)
8^th Week	MIDTERM WEEK
9^th Week	Definition of biocompability, immunology and biocompability tests for invasive medical devices
10^th Week	In vitro tests (Cytotoxicity test, simulations)
11^th Week	Animal Experiments (ethics and protocols)
12^th Week	Biocompability and Ethics
13^th Week	Case Study I: Biocompability tests for medical device
14^th Week	Case Study II: Biocompability tests for biomaterials

Recommended or Required Reading

ASM Handbook, Vol 10. Materials characterization, ASM International, 1990.
Elements of X-Ray Diffraction, 3rd ed., B.D. Cullity, Prentice Hall, 2001.
Biological Performance of Materials: Fundamentals of Biocompatibility, 2006, Jonathan Black, CRC Press Taylor & Francis Group,USA, ISBN 9780849339592,

Planned Learning Activities and Teaching Methods

Lecture
Discussion
Questions/Answers
Problem Solving

Assessment Methods and Criteria

	Quantity	Percentage (%)
Mid-term	1	30
Quiz	1	25
Attendance	1	5
Total(%)		60
Contribution of In-term Studies to Overall Grade(%)		60
Contribution of Final Examination to Overall Grade(%)		40
Total(%)		100

Language of Instruction

Turkish

Work Placement(s)

Programme Qualifications / Learning Outcomes

	LO1	LO2	LO3	LO4	LO5
K1	X	X	X	X
K2
K3
K4	X	X	X	X
K5
K6
K7					X
K8	X	X	X	X
K9
K10
K11