| Course Type | Elective Course |
|---|
| Course Level | Master's Degree With Thesis |
|---|
| Year of Study | - |
|---|
| Semester | - |
|---|
| ECTS | 10 |
|---|
| Name of Lecturer(s) |
- |
| Learning Outcomes |
At the end of this course, the students;
- Know how to evaluate bioreactor operation mode alternatives, build a mathematical model to be used in bioreactor design, and prepare an experimental execution plan.
- Know how to analyze bioreactor experimental execution results using informatics technologies, and calculate optimum values for system parameters using mathematical modeling.
- Know how to evaluate purification method alternatives, carry out accelerated shelf-life testing study, and prepare design outputs in report or presentation format using informatics technologies.
|
| Mode of Delivery | Face to face |
|---|
| Prerequisites | No |
|---|
| Recommended Optional Programme Components | Biotechnology |
|---|
| Course Description | In this course, bioengineering approaches in molecular biology are explained discussing bioreactor/fermenter design/scale-up, sterilization/thermal death kinetics of microorganisms, kinetics of biological reactions, enzyme kinetics, immobilized biocatalysts, kinetics of microbial growth, batch versus continuous operations, heat transfer/mass transfer in bioprocessing, product recovery/downstream processing, and bioprocess economics. |
|---|
| Course Contents |
| WEEK |
TOPICS |
|
1st Week |
Bioengineering approaches in molecular biology |
|
2nd Week |
Bioreactor/fermenter design/scale-up |
|
3rd Week |
Sterilization/thermal death kinetics of microorganisms |
|
4th Week |
Kinetics of biological reactions |
|
5th Week |
Enzyme kinetics |
|
6th Week |
Immobilized biocatalysts |
|
7th Week |
Kinetics of microbial growth |
|
8th Week |
Batch versus continuous operations |
|
9th Week |
Heat transfer/mass transfer in bioprocessing |
|
10th Week |
Heat transfer/mass transfer in bioprocessing |
|
11th Week |
Product recovery/downstream processing |
|
12th Week |
Product recovery/downstream processing |
|
13th Week |
Bioprocess economics |
|
14th Week |
Discussion |
|
| Recommended or Required Reading | Kim Gail Clarke, 2013, Bioprocess Engineering: An Introductory Engineering and Life Science Approach, Woodhead Publishing |
|---|
| Planned Learning Activities and Teaching Methods |
- Lecture
- Discussion
- Questions/Answers
- Case Study
- Project
- Report Preparation
- Presentation
|
|---|
| Assessment Methods and Criteria |
|
Quantity |
Percentage (%) |
| Mid-term |
1 |
35 |
| Project |
1 |
25 |
| Total(%) |
|
60 |
| Contribution of In-term Studies to Overall Grade(%) |
|
60 |
| Contribution of Final Examination to Overall Grade(%) |
|
40 |
| Total(%) |
|
100 |
|
| ECTS Allocated Based on Student Workload |
| Activities |
Quantity |
Duration (Hour) |
Total Workload (Hour) |
| Midterm exam |
1 |
2 |
2 |
| Preparation for Quiz |
|
|
|
| Individual or group work |
|
|
|
| Preparation for Final exam |
1 |
100 |
100 |
| Course hours |
14 |
3 |
42 |
| Preparation for Midterm exam |
1 |
90 |
90 |
| Laboratory (including preparation) |
|
|
|
| Final exam |
1 |
2 |
2 |
| Homework |
|
|
|
| Project |
1 |
65 |
65 |
| Total Work Load | 301 |
| Total Work Load / 30 (h) | 10.03 |
| ECTS Credit of the Course | 10 |
|
| Language of Instruction | English |
|---|
| Work Placement(s) | No |
|---|
