| Course Type | Elective Course |
|---|
| Course Level | Master's Degree With Thesis |
|---|
| Year of Study | - |
|---|
| Semester | - |
|---|
| ECTS | 10 |
|---|
| Name of Lecturer(s) |
- |
| Learning Outcomes |
At the end of this course, the students;
- Learn concepts of natural, synthetic, and semi-synthetic bioactive compounds, principles of extracting natural bioactive compounds, and biotechnology approaches in bioactive compound modification.
- Understand basic strategies in development of targeted new molecules with known indications, biosimilar concept, good laboratory and manufacture practices.
- Recognize strategies and applications from research and development phase to an authorized drug formulation.
|
| Mode of Delivery | Face to face |
|---|
| Prerequisites | No |
|---|
| Recommended Optional Programme Components | No |
|---|
| Course Description | Within the scope of this course; Definitions of natural, synthetic and semi-synthetic bioactive components, basic principles of obtaining bioactive components of natural origin and biotechnological approaches in the modification of bioactive components, basic approaches in the development of new molecules targeted for indications, the concept of biosimilars, and good laboratory and production practices are explained. |
|---|
| Course Contents |
| WEEK |
TOPICS |
|
1st Week |
Introduction and Basic Concepts |
|
2nd Week |
Concepts of natural, synthetic, and semi-synthetic bioactive compounds |
|
3rd Week |
Principles of extracting natural bioactive compounds |
|
4th Week |
Biotechnology approaches in bioactive compound modification Pharmaceutical Applications |
|
5th Week |
Basic strategies in development of targeted new molecules with known indications |
|
6th Week |
Literature discussions |
|
7th Week |
Biosimilar concept |
|
8th Week |
MIDTERM |
|
9th Week |
Drug Formulations |
|
10th Week |
GLP and GMP Concepts |
|
11th Week |
Phase Studies |
|
12th Week |
Patent Issues |
|
13th Week |
Recognition of Developed Drugs by Health Authorities |
|
14th Week |
Student presentations |
|
| Recommended or Required Reading | Modern Literature. / Update literature covering the studies in the area.
Molecular Biotechnology, Principles and Applications of Recombinant DNA. Bernard R. Glick, Jack J. Pasternak, ASM Press, Washington, D.C., 2009.
|
|---|
| Planned Learning Activities and Teaching Methods |
- Lecture
- Discussion
- Questions/Answers
- Presentation
|
|---|
| Assessment Methods and Criteria |
|
Quantity |
Percentage (%) |
| Mid-term |
1 |
35 |
| Assignment |
1 |
20 |
| Total(%) |
|
55 |
| Contribution of In-term Studies to Overall Grade(%) |
|
55 |
| Contribution of Final Examination to Overall Grade(%) |
|
45 |
| Total(%) |
|
100 |
|
| ECTS Allocated Based on Student Workload |
| Activities |
Quantity |
Duration (Hour) |
Total Workload (Hour) |
| Midterm exam |
1 |
84 |
84 |
| Preparation for Quiz |
1 |
16 |
16 |
| Individual or group work |
0 |
0 |
0 |
| Preparation for Final exam |
1 |
24 |
24 |
| Course hours |
14 |
3 |
42 |
| Preparation for Midterm exam |
1 |
11 |
11 |
| Laboratory (including preparation) |
0 |
0 |
0 |
| Final exam |
1 |
96 |
96 |
| Homework |
1 |
12 |
12 |
| Project |
1 |
12 |
12 |
| Total Work Load | 297 |
| Total Work Load / 30 (h) | 9.9 |
| ECTS Credit of the Course | 10 |
|
| Language of Instruction | Turkish |
|---|
| Work Placement(s) | No |
|---|
