| Course Type | Elective Course |
|---|
| Course Level | Bachelor's Degree |
|---|
| Year of Study | - |
|---|
| Semester | - |
|---|
| ECTS | 4 |
|---|
| Name of Lecturer(s) |
- |
| Learning Outcomes |
At the end of this course, the students;
- Evaluate oxidative stress formation processes by learning basic information about free radicals.
- Evaluate the mechanisms of the antioxidative defense system in response to free radicals by learning the basic information about antioxidants.
- Interpret the oxidative damage status in biological systems using the knowledge learned about the measurement methods of reactive species.
- Interpret the relationship of nutrition, disease and aging processes with free radicals and antioxidants.
|
| Mode of Delivery | Face to face |
|---|
| Prerequisites | No |
|---|
| Recommended Optional Programme Components | None |
|---|
| Course Description | This course aims to understand oxidative stress and antioxidant defense mechanisms in biological systems, as well as their relationship with diseases and aging, by providing basic information about free radicals and antioxidants. |
|---|
| Course Contents |
| WEEK |
TOPICS |
|
1st Week |
Introduction to the course and general concepts of the course |
|
2nd Week |
Free radicals |
|
3rd Week |
Basic principles of oxidative stress |
|
4th Week |
Oxidative damage mechanisms at cellular level-I: effects on DNA and RNA |
|
5th Week |
Oxidative damage mechanisms at cellular level-II: effects on lipids, proteins and carbohydrates |
|
6th Week |
Antioxidants synthesized in vivo |
|
7th Week |
Antioxidants from the diet |
|
8th Week |
Measurement of reactive species |
|
9th Week |
Reactive species: special problems and solutions |
|
10th Week |
Reactive species in disease |
|
11th Week |
Role for antioxidants in ageing, nutrition, disease, and therapy |
|
12th Week |
Paper Presentation |
|
13th Week |
Paper Presentation |
|
14th Week |
Discussion |
|
| Recommended or Required Reading | Free Radicals in Biology and Medicine. Barry Halliwell and John M. C. Gutteridge. Fifth Edition. Oxford University Press. 2015.
Oxidative Stress and the Molecular Biology of Antioxidant Defences, J. G. Scandolios, Cold Springer Harbour, NY, 1997.
Research articles |
|---|
| Planned Learning Activities and Teaching Methods |
- Lecture
- Discussion
- Presentation
|
|---|
| Assessment Methods and Criteria |
|
Quantity |
Percentage (%) |
| Mid-term |
1 |
30 |
| Presentation of Article |
1 |
15 |
| Total(%) |
|
45 |
| Contribution of In-term Studies to Overall Grade(%) |
|
45 |
| Contribution of Final Examination to Overall Grade(%) |
|
55 |
| Total(%) |
|
100 |
|
| ECTS Allocated Based on Student Workload |
| Activities |
Quantity |
Duration (Hour) |
Total Workload (Hour) |
| Midterm exam |
1 |
2 |
2 |
| Preparation for Quiz |
|
|
|
| Individual or group work |
|
|
|
| Preparation for Final exam |
1 |
35 |
35 |
| Course hours |
14 |
3 |
42 |
| Preparation for Midterm exam |
1 |
30 |
30 |
| Laboratory (including preparation) |
|
|
|
| Final exam |
1 |
2 |
2 |
| Homework |
|
|
|
| Article Presentation |
1 |
10 |
10 |
| Total Work Load | 121 |
| Total Work Load / 30 (h) | 4.03 |
| ECTS Credit of the Course | 4 |
|
| Language of Instruction | Turkish |
|---|
| Work Placement(s) | No |
|---|
