FUNCTIONAL GENOMICS

MBG419

Course Code: MBG419
Semester: -
Theory+Practice: 3 + 0
ECTS: 4

Course Type

Elective Course

Course Level

Bachelor's Degree

Year of Study

Semester

ECTS

Name of Lecturer(s)

Instructor Selin Akad Dinçer

Learning Outcomes

At the end of this course, the students;

Understand content of functional genomics, physical mapping of the genome and sequence analysis technologies.
Learn functional genomic applications for diagnosis of genetic diseases.
Understand gene identification, genome annotation and comparative genomic approaches using bioinformatics tools.
Understand integrative genomics and systems biology, and meta-genomics approaches.
Perform literature review on a topic of interest of the course content, and discuss results.

Mode of Delivery

Face to face

Prerequisites

Recommended Optional Programme Components

Course Description

The aim of this course is to introduce the methods used in bioinformatics and functional genomics. This course will discuss how eukaryotic organisms respond to various conditions at the whole genome level.

Course Contents

WEEK	TOPICS
1^st Week	Definition and Scope of Functional Genomics
2^nd Week	Genome Organization and Structure
3^rd Week	Genome regulatory mechanisms
4^th Week	DNA Repair Mechanisms
5^th Week	Genome Mapping
6^th Week	Genetic Diseases and Applications of Functional Genomics
7^th Week	Genome Editing Technologies
8^th Week	Genome Editing Technologies
9^th Week	Gene Identification
10^th Week	Bioinformatics and Genome Annotation Strategies
11^th Week	Comparative Genomics
12^th Week	Integrated Genomics and Systems Biology
13^th Week	Metagenomics
14^th Week	Student Projects and Discussions

Recommended or Required Reading

Principles of Gene Manipulation and Genomics, 7th Edition. S.B. Primrose and R.M. Twyman. Blackwell Publishing, 2006
Thompson & Thompson Genetics in Medicine. Robert L. Nussbaum, Roderick R. McInnes, Huntington F Willard. 9th, 2023
Temel ve İleri Moleküler Biyoloji Yöntemleri Genomik ve Proteomik Analizler. Temizkan G, Arda N. Nobel Tıp Kitapevleri
Scientific articles

Planned Learning Activities and Teaching Methods

Lecture
Discussion
Project
Presentation

Assessment Methods and Criteria

	Quantity	Percentage (%)
Mid-term	1	35
Project	1	15
Attendance	1	5
Total(%)		55
Contribution of In-term Studies to Overall Grade(%)		55
Contribution of Final Examination to Overall Grade(%)		45
Total(%)		100

ECTS Allocated Based on Student Workload

Activities	Quantity	Duration (Hour)	Total Workload (Hour)
Midterm exam	1	2	2
Preparation for Quiz
Individual or group work
Preparation for Final exam	1	30	30
Course hours	14	3	42
Preparation for Midterm exam	1	25	25
Laboratory (including preparation)
Final exam	1	2	2
Homework	1	20	20
Project
Total Work Load			121
Total Work Load / 30 (h)			4.03
ECTS Credit of the Course			4

Language of Instruction

Turkish

Work Placement(s)

Programme Qualifications / Learning Outcomes

	LO1	LO2	LO3	LO4	LO5
K1
K2	X	X	X	X	X
K3
K4
K5			X	X	X
K6					X
K7					X
K8	X	X	X	X	X
K9	X	X	X	X	X
K10	X	X	X	X	X
K11					X
K12					X
K13

	LO1	LO2	LO3	LO4	LO5
K1
K2	X	X	X	X	X
K3
K4
K5			X	X	X
K6					X
K7					X
K8	X	X	X	X	X
K9	X	X	X	X	X
K10	X	X	X	X	X
K11					X
K12					X
K13

	LO1	LO2	LO3	LO4	LO5
K1
K2	X	X	X	X	X
K3
K4
K5			X	X	X
K6					X
K7					X
K8	X	X	X	X	X
K9	X	X	X	X	X
K10	X	X	X	X	X
K11					X
K12					X
K13

	LO1	LO2	LO3	LO4	LO5
K1
K2	X	X	X	X	X
K3
K4
K5			X	X	X
K6					X
K7					X
K8	X	X	X	X	X
K9	X	X	X	X	X
K10	X	X	X	X	X
K11					X
K12					X
K13