MOLECULAR MECHANISMS IN NEURODEGENERATION

MBIO666

Course Code: MBIO666
Semester: -
Theory+Practice: 2 + 0
ECTS: 10

Course Type

Elective Course

Course Level

Doctorate Of Science

Year of Study

Semester

ECTS

Name of Lecturer(s)

Learning Outcomes

At the end of this course, the students;

explain molecular mechanisms in neurodegeneration
comprehend importance of molecular approach in current therapy protocols

Mode of Delivery

Face to face

Prerequisites

Recommended Optional Programme Components

Course Description

Course Contents

WEEK	TOPICS
1^st Week	What is neurodegeneration?
2^nd Week	Free radicals, oxidants and antioxidants
3^rd Week	Cellular metabolism, mitochondrial function and effects of oxidative damage
4^th Week	Calcium and neurodegeneration
5^th Week	Excitotoxicity
6^th Week	Neuroinflammation
7^th Week	Protein agregation and cellular defence sytytem
8^th Week	Class discussion with the recent review articles
9^th Week	Class discussion with the recent review articles
10^th Week	Class discussion with the recent review articles
11^th Week	Class discussion with the recent review articles
12^th Week	Class discussion with the recent review articles
13^th Week	Class discussion with the recent review articles
14^th Week	Class discussion with the recent review articles

Recommended or Required Reading

1. Cooper, Geoffrey M, The Cell - A Molecular Approach Sunderland (MA): Sinauer Associates, Inc.; c2000
2. Brown, T.A., Genomes,New York and London: Garland Science ; c2002
3. Strachan, Tom and Read, Andrew P., 3Human Molecular Genetics 2, New York and London: Garland Science; 2003
4. Alberts, Bruce; Johnson, Alexander; Lewis, Julian; Raff, Martin; Roberts, Keith; Walter, PeterMolecular Biology of the Cell, New York and London: Garland Science; c2002
5. Lodish, Harvey; Berk, Arnold; Zipursky, S. Lawrence; Matsudaira, Paul; Baltimore, David; Darnell, James E. Molecular Cell Biology,New York: W. H. Freeman & Co..2006

Planned Learning Activities and Teaching Methods

Lecture
Discussion
Questions/Answers

Assessment Methods and Criteria

	Quantity	Percentage (%)
Mid-term	1	40
Total(%)		40
Contribution of In-term Studies to Overall Grade(%)		40
Contribution of Final Examination to Overall Grade(%)		60
Total(%)		100

ECTS Allocated Based on Student Workload

Activities	Quantity	Duration (Hour)	Total Workload (Hour)
Midterm exam	1	2.5	2.5
Preparation for Quiz	0	0	0
Individual or group work	14	12	168
Preparation for Final exam	1	40	40
Course hours	14	2	28
Preparation for Midterm exam	1	35	35
Laboratory (including preparation)	0	0	0
Final exam	1	2.5	2.5
Homework	3	7.5	22.5
Total Work Load			298.5
Total Work Load / 30 (h)			9.95
ECTS Credit of the Course			10

Language of Instruction

Turkish

Work Placement(s)

Programme Qualifications / Learning Outcomes

	LO1	LO2
K1		X
K2		X
K3		X
K4		X
K5		X
K6		X
K7		X
K8		X
K9		X
K10		X
K11		X