| Course Type | Elective Course |
|---|
| Course Level | Doctorate Of Science |
|---|
| Year of Study | - |
|---|
| Semester | - |
|---|
| ECTS | 10 |
|---|
| Name of Lecturer(s) |
|
| Learning Outcomes |
At the end of this course, the students;
- Discuss molecules that affect metastatic and invasive processes of cancer cell
|
| Mode of Delivery | Face to face |
|---|
| Prerequisites | No |
|---|
| Recommended Optional Programme Components | |
|---|
| Course Description | The molecular basis of metastasis and invasion will be discussed. |
|---|
| Course Contents |
| WEEK |
TOPICS |
|
1st Week |
Course description and content |
|
2nd Week |
Extracellular matrix |
|
3rd Week |
Remodeling of the extracellular matrix in invasion |
|
4th Week |
Cell binding proteins, cellular connections and invasion |
|
5th Week |
Epithelial mesenchymal Transition |
|
6th Week |
Epithelial mesenchymal Transition |
|
7th Week |
Metastasis and angiogenesis |
|
8th Week |
Metastasis and angiogenesis |
|
9th Week |
Metastasis and lymphangiogenesis |
|
10th Week |
Therapeutic potential of angiogenesis for metastasis |
|
11th Week |
Organ-specific metastasis |
|
12th Week |
Metastatic pathways and processes |
|
13th Week |
Metastatic regulators |
|
14th Week |
"Seed" and "soil" |
|
15th Week |
|
|
| Recommended or Required Reading | 1. Brown, T.A Genomes (4th ed), New York and London: Garland Science, 2018
2. Strachan, Tom and Read, Andrew P., Human Molecular Genetics (4th ed), New York and London: Garland Science; 2012
3. Robert Weinberg, The Biology of Cancer (2nd Ed).2014. Garland Science: New York.
|
|---|
| Planned Learning Activities and Teaching Methods |
- Lecture
- Discussion
- Questions/Answers
|
|---|
| Assessment Methods and Criteria |
|
Quantity |
Percentage (%) |
| Mid-term |
1 |
40 |
| Total(%) |
|
40 |
| Contribution of In-term Studies to Overall Grade(%) |
|
40 |
| Contribution of Final Examination to Overall Grade(%) |
|
60 |
| Total(%) |
|
100 |
|
| ECTS Allocated Based on Student Workload |
| Activities |
Quantity |
Duration (Hour) |
Total Workload (Hour) |
| Midterm exam |
1 |
2.5 |
2.5 |
| Preparation for Quiz |
0 |
0 |
0 |
| Individual or group work |
14 |
12 |
168 |
| Preparation for Final exam |
1 |
50 |
50 |
| Course hours |
14 |
2 |
28 |
| Preparation for Midterm exam |
1 |
45 |
45 |
| Laboratory (including preparation) |
0 |
0 |
0 |
| Final exam |
1 |
2.5 |
2.5 |
| Homework |
1 |
2.5 |
2.5 |
| Total Work Load | 298.5 |
| Total Work Load / 30 (h) | 9.95 |
| ECTS Credit of the Course | 10 |
|
| Language of Instruction | Turkish |
|---|
| Work Placement(s) | No |
|---|
