CELL SIGNAL TRANSDUCTION

MBIO660

Course Code: MBIO660
Semester: -
Theory+Practice: 2 + 0
ECTS: 10

Course Type

Elective Course

Course Level

Doctorate Of Science

Year of Study

Semester

ECTS

Name of Lecturer(s)

Learning Outcomes

At the end of this course, the students;

Explains the basic signal transduction systems of the cell
Discuss the changes of signal transduction in the cancer process

Mode of Delivery

Face to face

Prerequisites

Recommended Optional Programme Components

Course Description

The important points of signal transduction in the cell in terms of cancer will be discussed.

Course Contents

WEEK	TOPICS
1^st Week	Structure and function of signal paths
2^nd Week	Nuclear receptors
3^rd Week	Signal with G-Protein Coupled Receptors
4^th Week	Signal with G-Protein Coupled Receptors
5^th Week	Tyrosine Kinase Respectors and Secondary Messengers
6^th Week	Serine / Threonine-specific protein Kinases
7^th Week	Protein phosphatases
8^th Week	Tyrosine protein kinases
9^th Week	RAS proteins
10^th Week	MAP kinases
11^th Week	Receptors associated with tyrosine kinase activity
12^th Week	Other receptor types
13^th Week	Article discussion
14^th Week	Article Discussion
15^th Week

Recommended or Required Reading

1. Brown, T.A Genomes (4th ed), New York and London: Garland Science, 2018
2. Strachan, Tom and Read, Andrew P., Human Molecular Genetics (4th ed), New York and London: Garland Science; 2012,
3. Robert Weinberg, The Biology of Cancer (2nd Ed).2014. Garland Science: New York.
4. Gerhard Krauss, Biochemistry of Signal Transduction and Regulation (4th Ed.), 2014 Wiley

Planned Learning Activities and Teaching Methods

Lecture
Discussion
Questions/Answers

Assessment Methods and Criteria

	Quantity	Percentage (%)
Mid-term	1	40
Total(%)		40
Contribution of In-term Studies to Overall Grade(%)		40
Contribution of Final Examination to Overall Grade(%)		60
Total(%)		100

ECTS Allocated Based on Student Workload

Activities	Quantity	Duration (Hour)	Total Workload (Hour)
Midterm exam	1	2.5	2.5
Preparation for Quiz	0	0	0
Individual or group work	14	12	168
Preparation for Final exam	1	45	45
Course hours	14	2	28
Preparation for Midterm exam	1	43	43
Laboratory (including preparation)	0	0	0
Final exam	1	2.5	2.5
Homework	2	5	10
Total Work Load			299
Total Work Load / 30 (h)			9.96
ECTS Credit of the Course			10

Language of Instruction

Turkish

Work Placement(s)

Programme Qualifications / Learning Outcomes

	LO1	LO2
K1		X
K2		X
K3		X
K4		X
K5		X
K6		X
K7		X
K8		X
K9		X
K10		X
K11		X