EPIGENETICS

MBIO658

Course Code: MBIO658
Semester: -
Theory+Practice: 2 + 0
ECTS: 10

Course Type

Elective Course

Course Level

Doctorate Of Science

Year of Study

Semester

ECTS

Name of Lecturer(s)

Learning Outcomes

At the end of this course, the students;

explain concept epigenetics
comprehend epigenetic mechnasims

Mode of Delivery

Face to face

Prerequisites

Recommended Optional Programme Components

Course Description

Course Contents

WEEK	TOPICS
1^st Week	Structure of DNA and RNA, chromatin and chromosome
2^nd Week	Three dimention structure of nucleus
3^rd Week	Inhertince patterns
4^th Week	Noncoding RNA
5^th Week	DNA methylation
6^th Week	Covalent histone modifications
7^th Week	Histone variants
8^th Week	Position effect
9^th Week	Dosage compensation
10^th Week	Epigenetic reprogramming
11^th Week	Genomic imprinting
12^th Week	Epigenetic and human diseases
13^th Week	Epigenetic and human diseases
14^th Week	Class discussion with the recent review articles

Recommended or Required Reading

1. Cooper, Geoffrey M, The Cell - A Molecular Approach Sunderland (MA): Sinauer Associates, Inc.; c2000
2. Brown, T.A., Genomes,New York and London: Garland Science ; c2002
3. Strachan, Tom and Read, Andrew P., 3Human Molecular Genetics 2, New York and London: Garland Science; 2003
4. Alberts, Bruce; Johnson, Alexander; Lewis, Julian; Raff, Martin; Roberts, Keith; Walter, PeterMolecular Biology of the Cell, New York and London: Garland Science; c2002
5. Lodish, Harvey; Berk, Arnold; Zipursky, S. Lawrence; Matsudaira, Paul; Baltimore, David; Darnell, James E. Molecular Cell Biology,New York: W. H. Freeman & Co..2006

Planned Learning Activities and Teaching Methods

Lecture
Discussion
Questions/Answers

Assessment Methods and Criteria

	Quantity	Percentage (%)
Mid-term	1	40
Total(%)		40
Contribution of In-term Studies to Overall Grade(%)		40
Contribution of Final Examination to Overall Grade(%)		60
Total(%)		100

ECTS Allocated Based on Student Workload

Activities	Quantity	Duration (Hour)	Total Workload (Hour)
Midterm exam	1	2.5	2.5
Preparation for Quiz	0	0	0
Individual or group work	14	12	168
Preparation for Final exam	1	50	50
Course hours	14	2	28
Preparation for Midterm exam	1	48	48
Laboratory (including preparation)	0	0	0
Final exam	1	2.5	2.5
Homework	1	2	2
Total Work Load			301
Total Work Load / 30 (h)			10.03
ECTS Credit of the Course			10

Language of Instruction

Turkish

Work Placement(s)

Programme Qualifications / Learning Outcomes

	LO1	LO2
K1		X
K2		X
K3		X
K4		X
K5		X
K6		X
K7		X
K8		X
K9		X
K10		X
K11		X