| Course Type | Elective Course |
|---|
| Course Level | Master's Degree With Thesis |
|---|
| Year of Study | - |
|---|
| Semester | - |
|---|
| ECTS | 9 |
|---|
| Name of Lecturer(s) |
|
| Learning Outcomes |
At the end of this course, the students;
- Learning humoral immunity techniques
- Learning to identify fluorescently labeled antibodies
- Learning to identify anti-HLA antibodies
- Learning antibody measurement methods
- Learning of antigen-antibody reactions
|
| Mode of Delivery | Face to face |
|---|
| Prerequisites | No |
|---|
| Recommended Optional Programme Components | TİM500
TİM531 |
|---|
| Course Description | In this course, humoral (secretory) mechanisms that play a role in transplantation immunology will be learned. |
|---|
| Course Contents |
| WEEK |
TOPICS |
|
1st Week |
Secretory Immune System Reactions in the Innate and Adaptive Immune System |
|
2nd Week |
Humoral Immunity Techniques |
|
3rd Week |
Determination of Antigen-Antibody Reactions in Transplantation |
|
4th Week |
Effects of Cytokines on Antibody Formation |
|
5th Week |
Monoclonal Antibody Generation Methods |
|
6th Week |
Homework Presentation |
|
7th Week |
Midterm |
|
8th Week |
Antibody Measurement Methods |
|
9th Week |
Anti-HLA Antibodies (Panel Reactive Antibodies) |
|
10th Week |
Single Antigen Identification |
|
11th Week |
The Importance of Anti-HLA Antibodies in Post-Transplant Follow-up |
|
12th Week |
Detection Methods of Autoantibodies |
|
13th Week |
Importance of Antigen-Antibody Reactions in Cross Match Tests |
|
14th Week |
Article Presentation |
|
| Recommended or Required Reading | Abbas A., Lichtman A., Pillai S., Cellular and Molecular Immunology, 10th edition, Elsevier, 2021
Roitt I., Brostoff J., Male D., Roth D, Male V, Immunology, 9th edition, Elsevier, 2020
Punt J, Stranford S., Jones P, Owen J. A., Kuby Immunology, 8th edition, W.H. Freeman, 2019 |
|---|
| Planned Learning Activities and Teaching Methods |
- Lecture
- Discussion
- Questions/Answers
- Presentation
- Practice
|
|---|
| Assessment Methods and Criteria |
|
Quantity |
Percentage (%) |
| Mid-term |
1 |
30 |
| Assignment |
1 |
10 |
| Presentation of Article |
1 |
10 |
| Total(%) |
|
50 |
| Contribution of In-term Studies to Overall Grade(%) |
|
50 |
| Contribution of Final Examination to Overall Grade(%) |
|
50 |
| Total(%) |
|
100 |
|
| ECTS Allocated Based on Student Workload |
| Activities |
Quantity |
Duration (Hour) |
Total Workload (Hour) |
| Midterm exam |
1 |
3 |
3 |
| Preparation for Quiz |
|
|
|
| Individual or group work |
14 |
7 |
98 |
| Preparation for Final exam |
1 |
50 |
50 |
| Course hours |
14 |
3 |
42 |
| Preparation for Midterm exam |
1 |
30 |
30 |
| Laboratory (including preparation) |
|
|
|
| Final exam |
1 |
3 |
3 |
| Homework |
1 |
20 |
20 |
| Article Presentation |
1 |
20 |
20 |
| Total Work Load | 266 |
| Total Work Load / 30 (h) | 8.86 |
| ECTS Credit of the Course | 9 |
|
| Language of Instruction | Turkish |
|---|
| Work Placement(s) | No |
|---|
