| Course Type | Elective Course |
|---|
| Course Level | Master's Degree With Thesis |
|---|
| Year of Study | - |
|---|
| Semester | - |
|---|
| ECTS | 9 |
|---|
| Name of Lecturer(s) |
|
| Learning Outcomes |
At the end of this course, the students;
- Identifying HLA tissue groups and learning their context and importance in transplantation
- Identifying anti-HLA antibodies and learning their context and importance in transplantation
- Cross Match tests and learning their context and importance in transplantation
- Immunomonitorization test and learning its context and importance in transplantation
|
| Mode of Delivery | Face to face |
|---|
| Prerequisites | No |
|---|
| Recommended Optional Programme Components | TİM500
TİM531 |
|---|
| Course Description | In this course, pre-transplant immunological preparation and follow-up of hematopoietic stem cell and solid organ transplantation candidates and donors, and planning, working and immunological evaluation of related tests will be learned. |
|---|
| Course Contents |
| WEEK |
TOPICS |
|
1st Week |
Determination of HLA Tissue Types |
|
2nd Week |
HLA Tissue Typing Tests (Molecular Low and High Resolution Typing) |
|
3rd Week |
The Role and Importance of HLA Tissue Types in Transplantation |
|
4th Week |
Detection of Anti-HLA Antibodies (PRA Screening/Identify/LSA/DSA) |
|
5th Week |
The Role and Importance of Anti-HLA Antibodies in Transplantation |
|
6th Week |
Importance of the Complement System in Transplantation |
|
7th Week |
C1q/C3d/C4d Determination Methods |
|
8th Week |
Midterm |
|
9th Week |
Homework Presentation |
|
10th Week |
Working of Cross Match Tests (Complement Dependent Cytotoxicity and Flow Cytometry Method) |
|
11th Week |
Importance of Cross Match Tests in Transplantation |
|
12th Week |
Working of Immunomonitorization Test and the Importance in Transplantation |
|
13th Week |
Case Discussion |
|
14th Week |
Case Discussion |
|
| Recommended or Required Reading | Abbas A., Lichtman A., Pillai S., Cellular and Molecular Immunology, 10th edition, Elsevier, 2021
Roitt I., Brostoff J., Male D., Roth D, Male V, Immunology, 9th edition, Elsevier, 2020
Punt J, Stranford S., Jones P, Owen J. A., Kuby Immunology, 8th edition, W.H. Freeman, 2019 |
|---|
| Planned Learning Activities and Teaching Methods |
- Lecture
- Discussion
- Questions/Answers
- Presentation
- Case Study
|
|---|
| Assessment Methods and Criteria |
|
Quantity |
Percentage (%) |
| Mid-term |
1 |
20 |
| Assignment |
1 |
10 |
| Presentation of Article |
1 |
10 |
| Presentation of Case Study |
1 |
10 |
| Total(%) |
|
50 |
| Contribution of In-term Studies to Overall Grade(%) |
|
50 |
| Contribution of Final Examination to Overall Grade(%) |
|
50 |
| Total(%) |
|
100 |
|
| ECTS Allocated Based on Student Workload |
| Activities |
Quantity |
Duration (Hour) |
Total Workload (Hour) |
| Midterm exam |
1 |
3 |
3 |
| Preparation for Quiz |
|
|
|
| Individual or group work |
14 |
7 |
98 |
| Preparation for Final exam |
1 |
50 |
50 |
| Course hours |
14 |
3 |
42 |
| Preparation for Midterm exam |
1 |
30 |
30 |
| Laboratory (including preparation) |
|
|
|
| Final exam |
1 |
3 |
3 |
| Homework |
1 |
20 |
20 |
| Article Presentation |
1 |
20 |
20 |
| Total Work Load | 266 |
| Total Work Load / 30 (h) | 8.86 |
| ECTS Credit of the Course | 9 |
|
| Language of Instruction | Turkish |
|---|
| Work Placement(s) | No |
|---|
