| Course Type | Elective Course |
|---|
| Course Level | Master's Degree With Thesis |
|---|
| Year of Study | - |
|---|
| Semester | - |
|---|
| ECTS | 9 |
|---|
| Name of Lecturer(s) |
|
| Learning Outcomes |
At the end of this course, the students;
- Learning immune system cells, tissues and organs
- Learning HLA structure and functions
- Learning the context and importance of HLA polymorphism and hematopoietic stem cell transplantation
- Learning the context and importance of HLA polymorphism and solid organ transplantation
- Learning the mechanism between HLA polymorphism and disease associations
|
| Mode of Delivery | Face to face |
|---|
| Prerequisites | No |
|---|
| Recommended Optional Programme Components | TİM500
TİM531 |
|---|
| Course Description | In this course, the cells and molecules of the immune system, the functions of HLA molecules, the importance of HLA polymorphism in hematopoietic stem cell and solid organ transplants, and the mechanisms between disease association will be discussed. |
|---|
| Course Contents |
| WEEK |
TOPICS |
|
1st Week |
Immune System Cells, Tissues and Organs |
|
2nd Week |
MHC and Antigen Presentation |
|
3rd Week |
HLA System and Polymorphism |
|
4th Week |
Determination Methods of HLA Molecules |
|
5th Week |
The Role and Importance of Polymorphic Structures in Antigen Presentation |
|
6th Week |
Immunological Tolerance |
|
7th Week |
Homework Presentation |
|
8th Week |
Midterm |
|
9th Week |
Cytokines |
|
10th Week |
Immunogenetic Mechanism in Behçet's Disease |
|
11th Week |
Immunogenetic Mechanism in Ankylosing Spondylitis Disease |
|
12th Week |
Immunogenetic Mechanism in Drug Reactions |
|
13th Week |
Case Presentation |
|
14th Week |
Case Presentation |
|
15th Week |
|
|
| Recommended or Required Reading | Abbas A., Lichtman A., Pillai S., Cellular and Molecular Immunology, 10th edition, Elsevier, 2021
Roitt I., Brostoff J., Male D., Roth D, Male V, Immunology, 9th edition, Elsevier, 2020
Punt J, Stranford S., Jones P, Owen J. A., Kuby Immunology, 8th edition, W.H. Freeman, 2019
|
|---|
| Planned Learning Activities and Teaching Methods |
- Lecture
- Discussion
- Questions/Answers
- Case Study
- Presentation
|
|---|
| Assessment Methods and Criteria |
|
Quantity |
Percentage (%) |
| Mid-term |
1 |
20 |
| Assignment |
1 |
10 |
| Presentation of Article |
1 |
10 |
| Presentation of Case Study |
1 |
10 |
| Total(%) |
|
50 |
| Contribution of In-term Studies to Overall Grade(%) |
|
50 |
| Contribution of Final Examination to Overall Grade(%) |
|
50 |
| Total(%) |
|
100 |
|
| ECTS Allocated Based on Student Workload |
| Activities |
Quantity |
Duration (Hour) |
Total Workload (Hour) |
| Midterm exam |
1 |
3 |
3 |
| Preparation for Quiz |
|
|
|
| Individual or group work |
14 |
7 |
98 |
| Preparation for Final exam |
1 |
50 |
50 |
| Course hours |
14 |
3 |
42 |
| Preparation for Midterm exam |
1 |
30 |
30 |
| Laboratory (including preparation) |
|
|
|
| Final exam |
1 |
3 |
3 |
| Homework |
1 |
20 |
20 |
| Article Presentation |
1 |
20 |
20 |
| Total Work Load | 266 |
| Total Work Load / 30 (h) | 8.86 |
| ECTS Credit of the Course | 9 |
|
| Language of Instruction | Turkish |
|---|
| Work Placement(s) | No |
|---|
