- Course Code
- TİM530
- Semester
- Second Term (Spring)
- Theory+Practice
- 3 + 0
- ECTS
- 9
| Course Type | Compulsory Course |
| Course Level | Master's Degree With Thesis |
| Year of Study | 1 |
| Semester | Second Term (Spring) |
| ECTS | 9 |
| Name of Lecturer(s) |
|
| Learning Outcomes |
At the end of this course, the students;
- Learning the humoral mechanisms involved in the innate immune system
- Learning the humoral mechanisms involved in the adaptive immune system
- Learning mediators that play a role in humoral system activation
- Understanding the importance of humoral mechanism in transplantation
|
| Mode of Delivery | Face to face |
| Prerequisites | No |
| Recommended Optional Programme Components | TİM500
TİM531
TİM532 |
| Course Description | In this course, humoral (secretory) mechanisms in the innate and adaptive immune system, cells involved in its activation, immune system mediators and the clinical importance of humoral mechanism in transplantation will be discussed. |
| Course Contents |
| WEEK |
TOPICS |
|
1st Week |
Investigation of the Humoral Mechanisms of the Innate Immune System |
|
2nd Week |
Investigation of the Humoral Mechanisms of the Adaptive Immune System |
|
3rd Week |
Inflammatory Cytokines |
|
4th Week |
Anti-inflammatory Cytokines |
|
5th Week |
Cytokines Involved in Immune Response Modulation |
|
6th Week |
Complement System and Activation |
|
7th Week |
The Importance of the Complement System and Activation in Transplantation |
|
8th Week |
Homework Presentation |
|
9th Week |
Midterm |
|
10th Week |
Determination of Complement Activation by Laboratory Methods |
|
11th Week |
Antibody Mediated Rejection Mechanisms |
|
12th Week |
The Clinical Significance of Complement-Activating Anti-HLA Antibodies |
|
13th Week |
Treatment Mechanisms in Antibody Mediated Rejections |
|
14th Week |
Article Presentation |
|
| Recommended or Required Reading | Abbas A., Lichtman A., Pillai S., Cellular and Molecular Immunology, 10th edition, Elsevier, 2021
Roitt I., Brostoff J., Male D., Roth D, Male V, Immunology, 9th edition, Elsevier, 2020
Punt J, Stranford S., Jones P, Owen J. A., Kuby Immunology, 8th edition, W.H. Freeman, 2019 |
| Planned Learning Activities and Teaching Methods |
- Lecture
- Discussion
- Questions/Answers
- Presentation
- Case Study
|
| Assessment Methods and Criteria |
|
Quantity |
Percentage (%) |
| Mid-term |
1 |
30 |
| Assignment |
1 |
10 |
| Presentation of Article |
1 |
10 |
| Total(%) |
|
50 |
| Contribution of In-term Studies to Overall Grade(%) |
|
50 |
| Contribution of Final Examination to Overall Grade(%) |
|
50 |
| Total(%) |
|
100 |
|
| ECTS Allocated Based on Student Workload |
| Activities |
Quantity |
Duration (Hour) |
Total Workload (Hour) |
| Midterm exam |
1 |
3 |
3 |
| Preparation for Quiz |
|
|
|
| Individual or group work |
14 |
7 |
98 |
| Preparation for Final exam |
1 |
50 |
50 |
| Course hours |
14 |
3 |
42 |
| Preparation for Midterm exam |
1 |
30 |
30 |
| Laboratory (including preparation) |
|
|
|
| Final exam |
1 |
3 |
3 |
| Homework |
1 |
20 |
20 |
| Article Presentation |
1 |
20 |
20 |
| Total Work Load | 266 |
| Total Work Load / 30 (h) | 8.86 |
| ECTS Credit of the Course | 9 |
|
| Language of Instruction | Turkish |
| Work Placement(s) | No |
Programme Qualifications / Learning Outcomes
|
LO1 |
LO2 |
LO3 |
LO4 |
| K1 |
|
|
|
|
| K2 |
X |
X |
X |
X |
| K3 |
|
|
|
|
| K4 |
|
|
|
|
| K5 |
X |
X |
|
|
| K6 |
X |
X |
X |
X |
| K7 |
|
|
|
|
| K8 |
|
|
|
|
| K9 |
X |
X |
X |
X |
| K10 |
X |
X |
X |
X |