| Course Type | Elective Course |
|---|
| Course Level | Master's Degree With Thesis |
|---|
| Year of Study | - |
|---|
| Semester | - |
|---|
| ECTS | 10 |
|---|
| Name of Lecturer(s) |
- |
| Learning Outcomes |
At the end of this course, the students;
- Learn human genetics and genetic disorders.
- Learn inheritance patterns of genetic diseases and molecular mechanisms of hereditary diseases.
- Learn GWAS, functional genomics and single-cell genomic technologies used in human genetics.
|
| Mode of Delivery | Face to face |
|---|
| Prerequisites | No |
|---|
| Recommended Optional Programme Components | Genetics |
|---|
| Course Description | In this course, human genetics and genetic disorders, heritability modes of genetic diseases, molecular mechanisms of inherited diseases, GWAS, functional genomics, and single-cell genomics technologies used in human genetics studies are covered. Students are required to discuss recent research articles in the area. |
|---|
| Course Contents |
| WEEK |
TOPICS |
|
1st Week |
Introduction to human genetics |
|
2nd Week |
Structure of DNA, RNA and protein |
|
3rd Week |
Molecular mechanisms (replication, transcription, translation, genetic code) |
|
4th Week |
Regulation of gene function and DNA repair mechanisms |
|
5th Week |
Human genome organization and chromosomal organization |
|
6th Week |
Mendelian and Non-mendelian inheritance |
|
7th Week |
Molecular basis of hereditary diseases and molecular disorders |
|
8th Week |
Genetic classification of diseases (chromosomal and single gene disorders) |
|
9th Week |
Genomics, proteomics and functional genomic technologies |
|
10th Week |
Gene therapy methods |
|
11th Week |
Functional genomics technology |
|
12th Week |
Single-cell technologies |
|
13th Week |
Student presentations and discussion on articles |
|
14th Week |
Student presentations and discussion on articles |
|
| Recommended or Required Reading | Human Molecular Genetics (5th Edition), Tom Strachan, Andrew Read, Garland Science, 2018.
Recent articles |
|---|
| Planned Learning Activities and Teaching Methods |
- Presentation
- Lecture
- Discussion
- Questions/Answers
|
|---|
| Assessment Methods and Criteria |
|
Quantity |
Percentage (%) |
| Mid-term |
1 |
25 |
| Presentation of Article |
1 |
20 |
| Presentation of Case Study |
1 |
10 |
| Total(%) |
|
55 |
| Contribution of In-term Studies to Overall Grade(%) |
|
55 |
| Contribution of Final Examination to Overall Grade(%) |
|
45 |
| Total(%) |
|
100 |
|
| ECTS Allocated Based on Student Workload |
| Activities |
Quantity |
Duration (Hour) |
Total Workload (Hour) |
| Midterm exam |
1 |
3 |
3 |
| Preparation for Quiz |
|
|
|
| Individual or group work |
|
|
|
| Preparation for Final exam |
1 |
100 |
100 |
| Course hours |
14 |
3 |
42 |
| Preparation for Midterm exam |
1 |
80 |
80 |
| Laboratory (including preparation) |
|
|
|
| Final exam |
1 |
3 |
3 |
| Homework |
|
|
|
| Presentation (including preperation) |
1 |
30 |
30 |
| Article Presentation |
1 |
45 |
45 |
| Total Work Load | 303 |
| Total Work Load / 30 (h) | 10.1 |
| ECTS Credit of the Course | 10 |
|
| Language of Instruction | English |
|---|
| Work Placement(s) | No |
|---|
