| Course Type | Elective Course |
|---|
| Course Level | Master's Degree With Thesis |
|---|
| Year of Study | - |
|---|
| Semester | - |
|---|
| ECTS | 10 |
|---|
| Name of Lecturer(s) |
- |
| Learning Outcomes |
At the end of this course, the students;
- Know the factors damaging the DNA and their mechanism of action.
- Know the mechanisms the cell evolved against these factors.
- Learn how accumulating damages in the cell cause genomic instability and learn the impact of the genomic stability on the cell survival and physiology.
- Learn new technologies in DNA repair and genomic instability fields.
- Students will be able to read and critically assess research papers relevant to the field of DNA repair and genome instability.
|
| Mode of Delivery | Face to face |
|---|
| Prerequisites | No |
|---|
| Recommended Optional Programme Components | No |
|---|
| Course Description | To investigate different DNA damage responses of the cell to protect its genomic stability, when it encounters DNA damage. |
|---|
| Course Contents |
| WEEK |
TOPICS |
|
1st Week |
Introduction-DNA damage |
|
2nd Week |
Cell cycle and checkpoints |
|
3rd Week |
Transcription |
|
4th Week |
Base excision repair, mismatch repair |
|
5th Week |
Nucleotide excision repair |
|
6th Week |
Double strand break repair |
|
7th Week |
DNA damage bypass |
|
8th Week |
Apoptosis and genomic instability |
|
9th Week |
Research paper presentation |
|
10th Week |
Research paper presentation |
|
11th Week |
Research paper presentation |
|
12th Week |
Research paper presentation |
|
13th Week |
Research paper presentation |
|
14th Week |
Research paper presentation |
|
| Recommended or Required Reading | Alberts, The Cell, 6th Edition
Recent articles
|
|---|
| Planned Learning Activities and Teaching Methods |
- Lecture
- Discussion
- Questions/Answers
- Presentation
- Case Study
- Problem Solving
|
|---|
| Assessment Methods and Criteria |
|
Quantity |
Percentage (%) |
| Mid-term |
1 |
40 |
| Attendance |
1 |
10 |
| Total(%) |
|
50 |
| Contribution of In-term Studies to Overall Grade(%) |
|
50 |
| Contribution of Final Examination to Overall Grade(%) |
|
50 |
| Total(%) |
|
100 |
|
| ECTS Allocated Based on Student Workload |
| Activities |
Quantity |
Duration (Hour) |
Total Workload (Hour) |
| Midterm exam |
1 |
3 |
3 |
| Preparation for Quiz |
|
|
|
| Individual or group work |
14 |
2 |
28 |
| Preparation for Final exam |
1 |
125 |
125 |
| Course hours |
14 |
3 |
42 |
| Preparation for Midterm exam |
1 |
100 |
100 |
| Laboratory (including preparation) |
|
|
|
| Final exam |
1 |
3 |
3 |
| Homework |
|
|
|
| Total Work Load | 301 |
| Total Work Load / 30 (h) | 10.03 |
| ECTS Credit of the Course | 10 |
|
| Language of Instruction | English |
|---|
| Work Placement(s) | No |
|---|
