| Course Type | Elective Course |
|---|
| Course Level | Master's Degree With Thesis |
|---|
| Year of Study | - |
|---|
| Semester | - |
|---|
| ECTS | 10 |
|---|
| Name of Lecturer(s) |
|
| Learning Outcomes |
At the end of this course, the students;
- Know different types of fetal and adult stromal tissue derived mesenchymal stem cells, and their isolation and characterization methods.
- Have a good knowledge of cell and molecular biology of mesenchymal stem cells, their usage in the field of bioengineering and regenerative medicine.
- Gain experience in literature search, presentation and discussion of current research articles or reviews about mesenchymal stem cells.
- Have scientific knowledge to create a research project about mesenchymal/stromal stem cells.
|
| Mode of Delivery | Face to face |
|---|
| Prerequisites | No |
|---|
| Recommended Optional Programme Components | Stem Cell Biology |
|---|
| Course Description | Molecular Biology of Stromal Stem Cell course gives information about the molecular biology, development, and behavior of different types of mesenchymal stem cells derived from fetal and adult stromal tissues. Also, it covers potential therapeutic applications of stromal/mesenchymal stem cells in the field of regenerative medicine and tissue engineering. It also describes the laboratory techniques that are used during stromal stem cell research. |
|---|
| Course Contents |
| WEEK |
TOPICS |
|
1st Week |
Introduction to mesenchymal stromal stem cells |
|
2nd Week |
The nomenclature of mesenchymal stromal cells |
|
3rd Week |
Current literature presentation and discussion about MSCs derived from fetal tissues |
|
4th Week |
The isolation and ex vivo expansion of mesenchymal stromal cells |
|
5th Week |
Current literature presentation and discussion about isolation and expansion of human MSCs |
|
6th Week |
The cell and molecular biology of mesenchymal stromal cells |
|
7th Week |
Current literature presentation and discussion about molecular biology of MSCs |
|
8th Week |
The role of mesenchymal stromal cells in the field of regenerative medicine |
|
9th Week |
Current literature presentation and discussion about MSCs as therapeutic agents |
|
10th Week |
The role of bioengineering in the therapeutic applications of mesenchymal stromal cells |
|
11th Week |
Current literature presentation and discussion about MSCs in the field of bioengineering |
|
12th Week |
GMP manufacturing of mesenchymal stromal cells for clinical use |
|
13th Week |
Project presentation |
|
14th Week |
Discussion |
|
| Recommended or Required Reading | Mesenchymal Stromal Cells, Translational Pathways to Clinical Adoption, Hematti Peiman, Sowmya Viswanathan, 1st Edition, 2016.
Current research articles and reviews |
|---|
| Planned Learning Activities and Teaching Methods |
- Lecture
- Discussion
- Questions/Answers
- Project
- Presentation
|
|---|
| Assessment Methods and Criteria |
|
Quantity |
Percentage (%) |
| Mid-term |
1 |
25 |
| Project |
1 |
20 |
| Presentation of Article |
1 |
20 |
| Total(%) |
|
65 |
| Contribution of In-term Studies to Overall Grade(%) |
|
65 |
| Contribution of Final Examination to Overall Grade(%) |
|
35 |
| Total(%) |
|
100 |
|
| ECTS Allocated Based on Student Workload |
| Activities |
Quantity |
Duration (Hour) |
Total Workload (Hour) |
| Midterm exam |
1 |
12 |
12 |
| Preparation for Quiz |
|
|
|
| Individual or group work |
|
|
|
| Preparation for Final exam |
1 |
24 |
24 |
| Course hours |
14 |
3 |
42 |
| Preparation for Midterm exam |
1 |
30 |
30 |
| Laboratory (including preparation) |
|
|
|
| Final exam |
1 |
12 |
12 |
| Homework |
|
|
|
| Presentation (including preperation) |
5 |
24 |
120 |
| Project |
1 |
60 |
60 |
| Total Work Load | 300 |
| Total Work Load / 30 (h) | 10 |
| ECTS Credit of the Course | 10 |
|
| Language of Instruction | English |
|---|
| Work Placement(s) | No |
|---|
