| Course Type | Elective Course |
|---|
| Course Level | Master's Degree With Thesis |
|---|
| Year of Study | - |
|---|
| Semester | - |
|---|
| ECTS | 10 |
|---|
| Name of Lecturer(s) |
- |
| Learning Outcomes |
At the end of this course, the students;
- learn gene delivery systems and methods.
- undertand and discuss the gene therapy approaches and starategies.
- learn the generation of transgenics and transgene analysis.
- learn and discuss the application areas of transgenics.
|
| Mode of Delivery | Face to face |
|---|
| Prerequisites | No |
|---|
| Recommended Optional Programme Components | Research Techniques for Molecular Biology and Genetics, Recombinant DNA Technology, Genetic Engineering |
|---|
| Course Description | This course covers information about requirements for gene expression in prokaryotes and eukaryotes, methods and techniques used to manipulate DNA, gene transfer methodologies, strategies for identifying and analyzing transgene, generation process of transgenic animals, the importance of transgenics in medicine and biotechnology, gene therapy applications, and current approaches to gene therapy. |
|---|
| Course Contents |
| WEEK |
TOPICS |
|
1st Week |
The history of gene therapy |
|
2nd Week |
Genetic manipulation |
|
3rd Week |
Gene transfer strategies |
|
4th Week |
Somatic gene therapy |
|
5th Week |
Germline gene therapy |
|
6th Week |
Applications and advances in gene therapy |
|
7th Week |
Ethical Issues in human gene transfer research |
|
8th Week |
Transgenic animals |
|
9th Week |
Production of transgenic animals |
|
10th Week |
Analysis of transgene expression |
|
11th Week |
Applications of transgenic animals in medicine |
|
12th Week |
Applications of transgenic animals in biotechnology |
|
13th Week |
Student presentations |
|
14th Week |
Student presentations |
|
| Recommended or Required Reading | Gene Cloning and Analysis: an introduction, 6th Edition. Brown, T.A. 2010.
The Development of Human Gene Therapy, Friedman, T. (1999) Cold Spring Harbor, NY: Cold Spring Harbor Lab.Press.
Transgenic Mouse: Methods and Protocols, Marten H. Hofker, Jan van Deursen, 2002. |
|---|
| Planned Learning Activities and Teaching Methods |
- Lecture
- Discussion
- Questions/Answers
- Presentation
|
|---|
| Assessment Methods and Criteria |
|
Quantity |
Percentage (%) |
| Assignment |
1 |
30 |
| Project |
1 |
45 |
| Presentation of Article |
1 |
25 |
| Total(%) |
|
100 |
| Contribution of In-term Studies to Overall Grade(%) |
|
100 |
| Contribution of Final Examination to Overall Grade(%) |
|
0 |
| Total(%) |
|
100 |
|
| ECTS Allocated Based on Student Workload |
| Activities |
Quantity |
Duration (Hour) |
Total Workload (Hour) |
| Midterm exam |
|
|
|
| Preparation for Quiz |
|
|
|
| Individual or group work |
|
|
|
| Preparation for Final exam |
|
|
|
| Course hours |
14 |
3 |
42 |
| Preparation for Midterm exam |
|
|
|
| Laboratory (including preparation) |
|
|
|
| Final exam |
|
|
|
| Homework |
1 |
50 |
50 |
| Project |
1 |
175 |
175 |
| Article Presentation |
1 |
35 |
35 |
| Total Work Load | 302 |
| Total Work Load / 30 (h) | 10.06 |
| ECTS Credit of the Course | 10 |
|
| Language of Instruction | English |
|---|
| Work Placement(s) | No |
|---|
