Information Package

Master's of Molecular Biology and Genetics with Thesis (English)

MBGE502

MOLECULAR EVOLUTION

Course Code
MBGE502
Semester
-
Theory+Practice
3 + 0
ECTS
10
Course TypeElective Course
Course LevelMaster's Degree With Thesis
Year of Study-
Semester-
ECTS10
Name of Lecturer(s) -
Learning Outcomes

At the end of this course, the students;

  1. Learn the basis of evolution at molecular and population.
  2. Learn the concepts of DNA and protein evolution and rate and pattern of molecular evolution.
  3. Learn molecular phylogenetic approaches and their applications.
  4. Learn how evolution takes place by means of gene duplications, molecular tinkering and mobile elements.
  5. Learn the mechanisms of prokaryotic and eukaryotic genom evolution and gene regulation.
Mode of DeliveryFace to face
PrerequisitesNo
Recommended Optional Programme ComponentsMolecular Genetics,Evolutionary Biology
Course DescriptionIn this course, the main evolutionary mechanisms at the molecular and genome levels affecting on the structure of genes, proteins and genomes are described. Molecular phylogenetic methods are included to study level and type of genetic variation at both genome and organismal level and deal with molecular data in order to test evolutionary hypothesis. In this content, this course links to evolutionary thinking to knowledge of molecular biology and genetics.
Course Contents
WEEK TOPICS
1st Week Introduction to molecular evolution
2nd Week The molecular basis of biology and evolution
3rd Week Allele dynamics in populations
4th Week DNA and amino acid sequence evolution
5th Week Paper discussion
6th Week Rates and patterns of molecular evolution
7th Week Molecular phylogenetics and phylogenetic trees
8th Week Reticulate evolution and phylogenetic networks
9th Week Evolution by DNA duplication
10th Week Paper discussion
11th Week Evolution by molecular tinkering
12th Week Mobile elements in evolution
13th Week Eukaryotic genome evolution
14th Week Paper discussion
Recommended or Required ReadingMolecular and Genome Evolution (2016) (First edition), Graur D., Oxford University Press.
Molecular Evolution, Statistical Approach (2014), Yang, Z., Oxford Scholarships Online.
Integrated Molecular Evolution (2016) (Second Edition), Rogers S.O., CRC Press,Taylor & Francis Group
Planned Learning Activities and Teaching Methods
  • Lecture
  • Discussion
  • Questions/Answers
  • Presentation
Assessment Methods and Criteria
Quantity Percentage (%)
Mid-term 1 35
Presentation of Article 2 30
Total(%) 65
Contribution of In-term Studies to Overall Grade(%) 65
Contribution of Final Examination to Overall Grade(%) 35
Total(%) 100
ECTS Allocated Based on Student Workload
Activities Quantity Duration (Hour) Total Workload (Hour)
Midterm exam 1 2 2
Preparation for Quiz
Individual or group work
Preparation for Final exam 1 85 85
Course hours 14 3 42
Preparation for Midterm exam 1 80 80
Laboratory (including preparation)
Final exam 1 2 2
Homework
Presentation (including preperation) 2 45 90
Total Work Load301
Total Work Load / 30 (h)10.03
ECTS Credit of the Course10
Language of InstructionEnglish
Work Placement(s)No
LO1 LO2 LO3 LO4 LO5
K1
K2 X X
K3 X X X X X
K4 X X X X X
K5
K6 X X X X X
K7 X X X X X
K8