| Course Type | Elective Course |
|---|
| Course Level | Bachelor's Degree |
|---|
| Year of Study | - |
|---|
| Semester | - |
|---|
| ECTS | 4 |
|---|
| Name of Lecturer(s) |
|
| Learning Outcomes |
At the end of this course, the students;
- Count the phases of the cell cycle.
- Use the terms of cell cycle phases, metabolisms and checkpoints correctly.
- Explain the formation processes of programmed and damage-related cell death types.
- Discuss the cell cycle and death in the context of different pathologies.
- Discuss drug development methods against cell cycle-derived cancers.
- Select the most appropriate analysis method and the methods used to analyze cell division and cell death under laboratory conditions.
|
| Mode of Delivery | Face to face |
|---|
| Prerequisites | No |
|---|
| Recommended Optional Programme Components | No |
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| Course Description | This course aims to enable the student to understand all the cell cycle components and mechanisms and the different mechanisms of cell death. |
|---|
| Course Contents |
| WEEK |
TOPICS |
|
1st Week |
Introduction, History and Basic Definitions |
|
2nd Week |
External Regulators of the Cell Cycle: Growth Factors |
|
3rd Week |
Internal Regulators of the Cell Cycle: Cyclins |
|
4th Week |
G1, G0, S, G2 Phases |
|
5th Week |
Mitosis |
|
6th Week |
Meiosis |
|
7th Week |
Discussion and Quiz |
|
8th Week |
Check Points of the Cell Cycle |
|
9th Week |
Cell Death and Types: Apoptosis and Necrosis |
|
10th Week |
Cell Death: Necroptosis, Pyroptosis and Autophagy |
|
11th Week |
Other Cell Death Mechanisms |
|
12th Week |
Cell Cycle Analysis Techniques |
|
13th Week |
Discussion and Quiz |
|
14th Week |
Course Overview |
|
| Recommended or Required Reading | Cellular Signal Processing: An Introduction to the Molecular Mechanisms of Signal Transduction 2nd Edition. Friedrich Marks, Ursula Klingmüller, Karin Müller-Decker. Garland Science 2017.
Molecular Cell Biology 8th Edition. Harvey Lodish, Arnold Berk , Chris A. Kaiser, Monty Krieger, Anthony Bretscher, Hidde Ploegh, Angelika Amon, Kelsey C. Martin. Macmillan Learning 2016. |
|---|
| Planned Learning Activities and Teaching Methods |
- Lecture
- Discussion
- Presentation
|
|---|
| Assessment Methods and Criteria |
|
Quantity |
Percentage (%) |
| Mid-term |
1 |
40 |
| Quiz |
2 |
20 |
| Total(%) |
|
60 |
| Contribution of In-term Studies to Overall Grade(%) |
|
60 |
| Contribution of Final Examination to Overall Grade(%) |
|
40 |
| Total(%) |
|
100 |
|
| ECTS Allocated Based on Student Workload |
| Activities |
Quantity |
Duration (Hour) |
Total Workload (Hour) |
| Midterm exam |
1 |
2 |
2 |
| Preparation for Quiz |
2 |
7 |
14 |
| Individual or group work |
|
|
|
| Preparation for Final exam |
1 |
35 |
35 |
| Course hours |
14 |
3 |
42 |
| Preparation for Midterm exam |
1 |
25 |
25 |
| Laboratory (including preparation) |
|
|
|
| Final exam |
1 |
2 |
2 |
| Homework |
|
|
|
| Article Presentation |
|
|
|
| Total Work Load | 120 |
| Total Work Load / 30 (h) | 4 |
| ECTS Credit of the Course | 4 |
|
| Language of Instruction | English |
|---|
| Work Placement(s) | No |
|---|
