| Course Type | Elective Course |
|---|
| Course Level | Bachelor's Degree |
|---|
| Year of Study | - |
|---|
| Semester | - |
|---|
| ECTS | 4 |
|---|
| Name of Lecturer(s) |
- |
| Learning Outcomes |
At the end of this course, the students;
- Learn the concepts and general information about pharmacogenetics.
- Learn the pathways of drug metabolism.
- Understand the mechanisms changing the action and bioavailability of drugs at the molecular level.
- Learn the genetic characteristics changing the effects of the drugs used for treatment and diagnosis.
|
| Mode of Delivery | Face to face |
|---|
| Prerequisites | No |
|---|
| Recommended Optional Programme Components | No |
|---|
| Course Description | The aim of this study is to discuss the changes in drug kinetics and the response of patients to drugs between individuals and ethnic groups according to genetic structure. |
|---|
| Course Contents |
| WEEK |
TOPICS |
|
1st Week |
Introduction to pharmacogenetics |
|
2nd Week |
Genetics and epigenetics in drug therapy |
|
3rd Week |
Drug Metabolism I |
|
4th Week |
Drug Metabolism II |
|
5th Week |
Pharmacogenetics of drug transporters |
|
6th Week |
Pharmacogenetics of drug targets |
|
7th Week |
Pharmacogenetics in cancer |
|
8th Week |
Pharmacogenetics in other disease |
|
9th Week |
High-throughput genotyping technologies for pharmacogenetic |
|
10th Week |
Modeling drug response |
|
11th Week |
Drug discovery |
|
12th Week |
Ethical and social issues in pharmacogenomics researching |
|
13th Week |
Pharmacogenetics: industry and regulatory affairs |
|
14th Week |
Discussion |
|
| Recommended or Required Reading | Pharmacogenetics And Individualized Therapy. Anke-Hilse Maitland-van der Zee, Ann K. Daly. Wiley Press. 2012.
Rang and Dale s Pharmacology, 7th. Edition, 2011.
The Cell: A Molecular Approach, Geoffrey M. Cooper and Robert E. Hausman, 5th Edition, 2009. |
|---|
| Planned Learning Activities and Teaching Methods |
- Lecture
- Questions/Answers
- Presentation
|
|---|
| Assessment Methods and Criteria |
|
Quantity |
Percentage (%) |
| Mid-term |
1 |
35 |
| Assignment |
1 |
10 |
| Attendance |
1 |
5 |
| Total(%) |
|
50 |
| Contribution of In-term Studies to Overall Grade(%) |
|
50 |
| Contribution of Final Examination to Overall Grade(%) |
|
50 |
| Total(%) |
|
100 |
|
| ECTS Allocated Based on Student Workload |
| Activities |
Quantity |
Duration (Hour) |
Total Workload (Hour) |
| Midterm exam |
1 |
2 |
2 |
| Preparation for Quiz |
|
|
|
| Individual or group work |
14 |
1 |
14 |
| Preparation for Final exam |
1 |
30 |
30 |
| Course hours |
14 |
3 |
42 |
| Preparation for Midterm exam |
1 |
20 |
20 |
| Laboratory (including preparation) |
|
|
|
| Final exam |
1 |
2 |
2 |
| Homework |
1 |
12 |
12 |
| Total Work Load | 122 |
| Total Work Load / 30 (h) | 4.06 |
| ECTS Credit of the Course | 4 |
|
| Language of Instruction | English |
|---|
| Work Placement(s) | No |
|---|
