Information Package

Program of Molecular Biology and Genetics (English)

MBGE424

EPIGENETICS

Course Code
MBGE424
Semester
-
Theory+Practice
3 + 0
ECTS
4
Course TypeElective Course
Course LevelBachelor's Degree
Year of Study-
Semester-
ECTS4
Name of Lecturer(s)
Learning Outcomes

At the end of this course, the students;

  1. Learn the basis of epigenetic.
  2. Learn the chromatin structure and the epigenetic mechanisms in terms of regulation of gene expression.
  3. Learn the used methods in epigenetics and epigenetic databases.
  4. Learn the latest technologies in the epigenetic field.
Mode of DeliveryFace to face
PrerequisitesNo
Recommended Optional Programme ComponentsNo
Course DescriptionExplaining the details of epigenetic mechanisms and their effects on gene regulation by changing the chromatin structure.
Course Contents
WEEK TOPICS
1st Week Introduction
2nd Week Introduction to Epigenetics, Biology of Chromatin, Epigenetic Modifications
3rd Week DNA Methylation, CpG Islands and Analyses
4th Week Histone Modifications and Analyses
5th Week Chromosomal Position Effect & Polycomb Mechanism & Epigenetics of noc-coding RNAs
6th Week Important Protein Structures in Epigenetics
7th Week Research Article Discussion I
8th Week Research Article Discussion II
9th Week Student Presentations
10th Week Student Presentations
11th Week Student Presentations
12th Week Student Presentations
13th Week Student Presentations
14th Week Course Overview
Recommended or Required ReadingIntroduction to Epigenetics by Renato Paro, Ueli Grossniklaus, Raffaella Santoro, Anton Wutz (Learning Materials in Biosciences, Springer) Handbook of Epigenetics 2th Edition by Trygve o Tollefsbol (Academic Press Elsevier)
Recent Review Articles
Planned Learning Activities and Teaching Methods
  • Lecture
  • Discussion
  • Questions/Answers
  • Presentation
Assessment Methods and Criteria
Quantity Percentage (%)
Mid-term 1 25
Presentation of Article 1 25
Other 1 10
Total(%) 60
Contribution of In-term Studies to Overall Grade(%) 60
Contribution of Final Examination to Overall Grade(%) 40
Total(%) 100
ECTS Allocated Based on Student Workload
Activities Quantity Duration (Hour) Total Workload (Hour)
Midterm exam 1 1.5 1.5
Preparation for Quiz
Individual or group work
Preparation for Final exam 1 30 30
Course hours 14 3 42
Preparation for Midterm exam 1 30 30
Laboratory (including preparation)
Final exam 1 1.5 1.5
Homework
Presentation (including preperation) 1 15 15
Total Work Load120
Total Work Load / 30 (h)4
ECTS Credit of the Course4
Language of InstructionEnglish
Work Placement(s)No
LO1 LO2 LO3 LO4
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K13