Information Package
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Program of Molecular Biology and Genetics (English)

MBGE422

ENZYMOLOGY

Course Code
MBGE422
Semester
-
Theory+Practice
3 + 0
ECTS
4
Course TypeElective Course
Course LevelBachelor's Degree
Year of Study-
Semester-
ECTS4
Name of Lecturer(s)
Learning Outcomes

At the end of this course, the students;

  1. Define and write the basic principles of enzymology, structures, and properties of enzymes and their regulation.
  2. Interpret their results in the context of principles and linking enzyme assay results to the specific physiological conditions, based on the well-known enzyme assays.
  3. Exemplify the factors affecting the enzyme activity and discuss each parameter.
  4. Know the potential applications of enzymes in diagnostic, industrial, and biotechnological applications can generate practical research ideas for future studies.
Mode of DeliveryFace to face
PrerequisitesNo
Recommended Optional Programme ComponentsNo
Course DescriptionAim of this course to cover enzymology, including enzyme properties, catalytic effects, classification, non-enzymatic biological catalysts, and well-known enzyme assays. It also emphasizes the significant role of enzymes in drug design and their potential applications in various fields, from industry to clinics.
Course Contents
WEEK TOPICS
1st Week Overview of enzymology
2nd Week General aspects of enzyme analysis
3rd Week Structures and properties of enzymes
4th Week Classification of the enzymes
5th Week Mechanism of enzyme catalysis and coenzymes
6th Week Enzyme assays (e.g., general literature for protein assays, enzyme immunoassays)
7th Week Factors affecting enzyme activity
8th Week Enzyme kinetics
9th Week Regulation of enzyme activity
10th Week Location of the enzymes in the cell
11th Week Enzymes in technical applications (modes and methods for enzyme immobilizations)
12th Week Clinical enzymology
13th Week Clinical enzymology and biotechnology of extremophilic enzymes
14th Week Comprehensive review of the course content
Recommended or Required ReadingLehninger Principles of Biochemistry. David L. Nelson, Michael M. Cox. W.H. Freeman, 7th Edition, 2017.
Fundamentals of Biochemistry: Life at the Molecular Level. Donald Voet, Judith G. Voet, Charlotte W. Pratt. Wiley, 5th Edition, 2016.
Molecular and Cellular Enzymology, Jeannine Yon-Kahn, G. Herve. Springer Berlin, Heidelberg, 2010.
Practical Enzymology, Hans Bisswanger, 3rd Edition,Wiley.
Planned Learning Activities and Teaching Methods
  • Lecture
  • Questions/Answers
  • Presentation
  • Discussion
  • Other
Assessment Methods and Criteria
Quantity Percentage (%)
Mid-term 1 35
Presentation of Article 1 20
Total(%) 55
Contribution of In-term Studies to Overall Grade(%) 55
Contribution of Final Examination to Overall Grade(%) 45
Total(%) 100
ECTS Allocated Based on Student Workload
Activities Quantity Duration (Hour) Total Workload (Hour)
Midterm exam 1 2 2
Preparation for Quiz
Individual or group work
Preparation for Final exam 1 30 30
Course hours 14 3 42
Preparation for Midterm exam 1 28 28
Laboratory (including preparation)
Final exam 1 2 2
Homework
Article Presentation 1 18 18
Total Work Load122
Total Work Load / 30 (h)4.06
ECTS Credit of the Course4
Language of InstructionEnglish
Work Placement(s)No

Programme Qualifications / Learning Outcomes

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