STEM CELL BIOLOGY

MBGE417

Course Code: MBGE417
Semester: -
Theory+Practice: 3 + 0
ECTS: 4

Course Type

Elective Course

Course Level

Bachelor's Degree

Year of Study

Semester

ECTS

Name of Lecturer(s)

Learning Outcomes

At the end of this course, the students;

Learn the description, general properties and the types of stem cells.
Learn the markers that specify the plasticity of stem cells.
The molecular mechanisms of self-renewal, proliferation, differentiation, dedifferentiation and senescence of stem cells.
Learn different types of stem cells; their sources, properties and applications in regenerative medicine.
Learn different types of niches that harbor the specific types of tissue / organ stem cells.
Learn the laboratory techniques (isolation, characterization, differentiation and molecular techniques and microscopic analyses) that are used during stem cell studies.

Mode of Delivery

Face to face

Prerequisites

Recommended Optional Programme Components

Course Description

Stem Cell Biology course gives information about the molecular mechanisms that regulate the development, function and the behavior of stem cells in their microenvironment (niche), types/stem cell and about the applications of stem cells in the field of regenerative medicine and tissue engineering. It also describes the laboratory techniques that are used during stem cell research.

Course Contents

WEEK	TOPICS
1^st Week	Course Introduction
2^nd Week	General Concepts in Stem Cell Biology
3^rd Week	Molecular Ragulators of Stem Cell Behaviour
4^th Week	Embryonic Stem Cells
5^th Week	Induced Pluripotent Stem Cells
6^th Week	Fetal Stem Cells
7^th Week	Stem Cell Niches
8^th Week	Mesenchymal Stem Cells
9^th Week	Hematopoietic Stem Cells
10^th Week	Other Tissue-Specific Stem Cells
11^th Week	Research Article Presentations
12^th Week	Research Article Presentations
13^th Week	Research Article Presentations
14^th Week	Research Article Presentations

Recommended or Required Reading

Essentials of Stem Cell Biology 3rd edition. John Gearhart, Brigid Hogan, Douglas Melton, Roger Pedersen, E. Donall Thomas, James Thomas, Sir Ian Wilmut.
Stem Cells, A Short Course. Rob Burgess. Wiley Blackwell.
The Science of Stem Cells. Jonathan M. W. Slack. Wiley Blackwell.
KÖK HÜCRE Biyolojisi, Türleri ve Tedavide Kullanımları (1. Basım), Alp Can, 2014.
Reviews and research articles

Planned Learning Activities and Teaching Methods

Lecture
Discussion
Questions/Answers
Presentation

Assessment Methods and Criteria

	Quantity	Percentage (%)
Mid-term	1	35
Presentation of Article	1	20
Total(%)		55
Contribution of In-term Studies to Overall Grade(%)		55
Contribution of Final Examination to Overall Grade(%)		45
Total(%)		100

ECTS Allocated Based on Student Workload

Activities	Quantity	Duration (Hour)	Total Workload (Hour)
Midterm exam	1	2	2
Preparation for Quiz
Individual or group work	14	1	14
Preparation for Final exam	1	27	27
Course hours	14	3	42
Preparation for Midterm exam	1	25	25
Laboratory (including preparation)
Final exam	1	2	2
Homework
Report writing	1	3	3
Article Presentation	1	7	7
Total Work Load			122
Total Work Load / 30 (h)			4.06
ECTS Credit of the Course			4

Language of Instruction

English

Work Placement(s)

Programme Qualifications / Learning Outcomes

	LO1	LO2	LO3	LO4	LO5	LO6
K1	X	X	X
K2	X	X	X
K3				X	X
K4				X	X	X
K5
K6				X	X
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K11
K12					X
K13				X

	LO1	LO2	LO3	LO4	LO5	LO6
K1	X	X	X
K2	X	X	X
K3				X	X
K4				X	X	X
K5
K6				X	X
K7	X	X	X		X
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K10					X
K11
K12					X
K13				X

	LO1	LO2	LO3	LO4	LO5	LO6
K1	X	X	X
K2	X	X	X
K3				X	X
K4				X	X	X
K5
K6				X	X
K7	X	X	X		X
K8					X
K9					X
K10					X
K11
K12					X
K13				X

	LO1	LO2	LO3	LO4	LO5	LO6
K1	X	X	X
K2	X	X	X
K3				X	X
K4				X	X	X
K5
K6				X	X
K7	X	X	X		X
K8					X
K9					X
K10					X
K11
K12					X
K13				X