| Course Type | Elective Course |
|---|
| Course Level | Bachelor's Degree |
|---|
| Year of Study | - |
|---|
| Semester | - |
|---|
| ECTS | 4 |
|---|
| Name of Lecturer(s) |
|
| Learning Outcomes |
At the end of this course, the students;
- Understand basic molecular mechanisms and data processing of signal transduction.
- Learn extracellular signals, cell receptors and secondary messengers.
- Learn sensory signal processing and signaling at synapses.
- Discuss basic signal transduction processes in relation to different pathological conditions.
|
| Mode of Delivery | Face to face |
|---|
| Prerequisites | No |
|---|
| Recommended Optional Programme Components | No |
|---|
| Course Description | In this course, intercellular communications, intracellular signal transduction pathways, and participation of these pathways in specific pathophysiologies are given. |
|---|
| Course Contents |
| WEEK |
TOPICS |
|
1st Week |
Data processing of the cell and networks |
|
2nd Week |
Molecular switches |
|
3rd Week |
Signal transduction by G-protein-coupled receptors and secondary messengers I |
|
4th Week |
Signal transduction by G-protein-coupled receptors and secondary messengers II |
|
5th Week |
Signal transduction by tyrosine kinase and secondary messengers I |
|
6th Week |
Signal transduction by tyrosine kinase and secondary messengers II |
|
7th Week |
Nuclear receptors |
|
8th Week |
Controlled proteolysis and signal transduction |
|
9th Week |
Sensory signaling pathways I |
|
10th Week |
Sensory signaling pathways II |
|
11th Week |
Circadian rhythm |
|
12th Week |
Discussion in relation to pathological conditions |
|
13th Week |
Discussion in relation to pathological conditions |
|
14th Week |
Summary and discussion |
|
| Recommended or Required Reading | Cellular Signal Processing: An Introduction to the Molecular Mechanisms of Signal Transduction 2nd Edition. Friedrich Marks, Ursula Klingmüller, Karin Müller-Decker. Garland Science 2017.
Cell Signaling: Principles and Mechanisms. 1st Edition. Lim, Mayer, Pawson. Garland Science 2017.
Molecular Biology of the Cell. 6th edition. Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter. |
|---|
| Planned Learning Activities and Teaching Methods |
- Presentation
- Lecture
- Discussion
- Questions/Answers
|
|---|
| Assessment Methods and Criteria |
|
Quantity |
Percentage (%) |
| Mid-term |
1 |
30 |
| Presentation of Article |
1 |
20 |
| Total(%) |
|
50 |
| Contribution of In-term Studies to Overall Grade(%) |
|
50 |
| Contribution of Final Examination to Overall Grade(%) |
|
50 |
| Total(%) |
|
100 |
|
| ECTS Allocated Based on Student Workload |
| Activities |
Quantity |
Duration (Hour) |
Total Workload (Hour) |
| Midterm exam |
1 |
2 |
2 |
| Preparation for Quiz |
|
|
|
| Individual or group work |
14 |
1 |
14 |
| Preparation for Final exam |
1 |
25 |
25 |
| Course hours |
14 |
3 |
42 |
| Preparation for Midterm exam |
1 |
20 |
20 |
| Laboratory (including preparation) |
|
|
|
| Final exam |
1 |
2 |
2 |
| Homework |
|
|
|
| Article Presentation |
1 |
16 |
16 |
| Total Work Load | 121 |
| Total Work Load / 30 (h) | 4.03 |
| ECTS Credit of the Course | 4 |
|
| Language of Instruction | English |
|---|
| Work Placement(s) | No |
|---|
