| Course Type | Elective Course |
|---|
| Course Level | Doctorate Of Science |
|---|
| Year of Study | - |
|---|
| Semester | - |
|---|
| ECTS | 10 |
|---|
| Name of Lecturer(s) |
|
| Learning Outcomes |
At the end of this course, the students;
- Be able to describe the concepts of the immune system
- Be able to describe the factors that play roles in the immune system
- Be able to describe the definition of an innate and adaptive immune system
- Be able to describe the mechanism of antigen recognition
- Be able to describe the mechanism of immunoglobulin diversity
- Be able to describe the mechanism of T cell receptor diversity
- Be able to describe the inherited diseases caused by immune system defects
- Be able to describe the relationship between acquired genetic diseases and the immune system
|
| Mode of Delivery | Face to face |
|---|
| Prerequisites | No |
|---|
| Recommended Optional Programme Components | None |
|---|
| Course Description | At the end of the course, students are expected to get basic information about innate and adaptive immunity, understand cellular components of immune system, antigen recognition, molecular mechanisms of antigen presentation, genetic basis of antibody diversity, rearrangement and expression of antigen receptor genes, effector mechanisms in cellular and humoral immunity, cytokines and tumor immunology. |
|---|
| Course Contents |
| WEEK |
TOPICS |
|
1st Week |
1. Immun system and its components |
|
2nd Week |
2. Innate immune system |
|
3rd Week |
3. Adaptive immune system |
|
4th Week |
4. Homologous recombination and gene rearrangement |
|
5th Week |
5. Immunoglobulin gene family |
|
6th Week |
6. B lymphocytes and immunoglobulins-discussion |
|
7th Week |
7. Mid Term |
|
8th Week |
8. Immuno-oncology |
|
9th Week |
9. CAR-T cells |
|
10th Week |
10. Immunogenetics and transplantation-lecture and recent literature |
|
11th Week |
11. Human Leukocyte Antigens (HLA) and recurrent pregnancy loss-lecture and recent literature |
|
12th Week |
12. Presentation |
|
13th Week |
13. Presentation |
|
14th Week |
14. Immunodeficiency disorders |
|
15th Week |
|
|
16th Week |
|
|
| Recommended or Required Reading | 1. Update literature covering the studies in the area.
2. Molecular Biology of the Cell. 6th edition. Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter.
3. Cellular and Molecular Immunology, 8th Edition. Abul K. Abbas, Andrew H. H. Lichtman, ShivPillai, 2015.
|
|---|
| Planned Learning Activities and Teaching Methods |
- Lecture
- Discussion
- Practice
- Report Preparation
- Project
- Presentation
|
|---|
| Assessment Methods and Criteria |
|
Quantity |
Percentage (%) |
| Mid-term |
1 |
30 |
| Assignment |
1 |
20 |
| Total(%) |
|
50 |
| Contribution of In-term Studies to Overall Grade(%) |
|
50 |
| Contribution of Final Examination to Overall Grade(%) |
|
50 |
| Total(%) |
|
100 |
|
| ECTS Allocated Based on Student Workload |
| Activities |
Quantity |
Duration (Hour) |
Total Workload (Hour) |
| Midterm exam |
1 |
2 |
2 |
| Preparation for Quiz |
2 |
3 |
6 |
| Individual or group work |
14 |
5 |
70 |
| Preparation for Final exam |
1 |
30 |
30 |
| Course hours |
14 |
3 |
42 |
| Preparation for Midterm exam |
1 |
20 |
20 |
| Laboratory (including preparation) |
|
|
|
| Final exam |
1 |
2 |
2 |
| Homework |
4 |
32 |
128 |
| Total Work Load | 300 |
| Total Work Load / 30 (h) | 10 |
| ECTS Credit of the Course | 10 |
|
| Language of Instruction | Turkish |
|---|
| Work Placement(s) | No |
|---|
