Information Package
baskent.edu.tr

Ph.D. on Medical Genetics

GEN625

CELLULAR SIGNAL TRANSDUCTION PATHWAYS

Course Code
GEN625
Semester
Third Term (Fall)Fourth Term (Spring)
Theory+Practice
2 + 0
ECTS
8
Course TypeCompulsory Course
Course LevelDoctorate Of Science
Year of Study2
SemesterThird Term (Fall)Fourth Term (Spring)
ECTS8
Name of Lecturer(s)
Learning Outcomes

At the end of this course, the students;

  1. Knows how cells communicate with each other
  2. Knows intracellular signal transduction pathways
  3. Knows how intracellular signal transduction pathways affect cell functions such as transcription, translation, intracellular protein traffic and cell proliferation.
  4. Knows the pathological conditions related to the deterioration of signal transmission.
Mode of DeliveryFace to face
PrerequisitesNo
Recommended Optional Programme ComponentsNone
Course DescriptionThe students are expected to understand sensing, integration and amplification of extracellular signals, generation and integration of cellular responses, changes in enzyme activities, gene expressions and protein properties as a response which in turn affect cellular proliferation, growth, motility and cell death. The student will also gain knowledge of pathologies caused by deregulation of integrated signaling circuits.
Course Contents The students are expected to understand sensing, integration and amplification of extracellular signals, generation and integration of cellular responses, changes in enzyme activities, gene expressions and protein properties as a response which in turn affect cellular proliferation, growth, motility and cell death. The student will also gain knowledge of pathologies caused by deregulation of integrated signaling circuits.
Recommended or Required Reading1 Molecular Biology of the Cell. Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter. 6th edition.
2. MolecularBiology of the Gene. James D. Watson, Tania A. Baker, Stephen P. Bell, Alexander Gann, Michael Levine. 7th Edition (2014).
3. Lewin's GENES XII. Jocelyn E. Krebs, Elliott S. Goldstein, Stephen T. Kilpatrick (2017).
Planned Learning Activities and Teaching Methods
  • Lecture
  • Discussion
  • Questions/Answers
  • Case Study
  • Problem Solving
  • Presentation
Assessment Methods and Criteria
Quantity Percentage (%)
Mid-term 1 30
Assignment 1 20
Total(%) 50
Contribution of In-term Studies to Overall Grade(%) 50
Contribution of Final Examination to Overall Grade(%) 50
Total(%) 100
ECTS Allocated Based on Student Workload
Activities Quantity Duration (Hour) Total Workload (Hour)
Midterm exam 1 2 2
Preparation for Quiz 2 3 6
Individual or group work 14 5 70
Preparation for Final exam 1 26 26
Course hours 14 3 42
Preparation for Midterm exam 1 20 20
Laboratory (including preparation)
Final exam 1 2 2
Homework 3 24 72
Total Work Load240
Total Work Load / 30 (h)8
ECTS Credit of the Course8
Language of InstructionTurkish
Work Placement(s)No

Programme Qualifications / Learning Outcomes

LO1 LO2 LO3 LO4
K1 X X X X
K2 X X X X
K3 X
K4 X
K5 X X X X
K6 X
K7 X X X X
K8 X X X X
K9 X X X X