| Course Type | Elective Course |
| Course Level | Bachelor's Degree |
| Year of Study | - |
| Semester | - |
| ECTS | 4 |
| Name of Lecturer(s) |
|
| Learning Outcomes |
At the end of this course, the students;
- Knows the external and internal regulators of the cell cycle.
- Knows the phases of the cell cycle and its checkpoints.
- Understands programmed and damage-induced cell death pathways and their regulation.
- Discuss the cell cycle and cell death in the context of different pathologies.
|
| Mode of Delivery | Face to face |
| Prerequisites | No |
| Recommended Optional Programme Components | None |
| Course Description | It is about the control of the cell life cycle, checkpoints, and their importance in apoptosis and cancer. |
| Course Contents |
| WEEK |
TOPICS |
|
1st Week |
Introduction |
|
2nd Week |
External and Internal Regulators of the Cell Cycle: Growth Factors and Cyclins |
|
3rd Week |
G1, G0, S, and G2 Phases |
|
4th Week |
Mitosis and Meiosis |
|
5th Week |
Checkpoints of the Cell Cycle |
|
6th Week |
Cell Death and Types of Death |
|
7th Week |
Cell Death: Apoptosis and Necrosis |
|
8th Week |
Cell Death: Necroptosis, Pyroptosis, Autophagy |
|
9th Week |
Analyses of Cell Cycle and Cell Death |
|
10th Week |
Presentations and Discussion |
|
11th Week |
Presentations and Discussion |
|
12th Week |
Presentations and Discussion |
|
13th Week |
Presentations and Discussion |
|
14th Week |
Presentations and Discussion |
|
| Recommended or Required Reading | Molecular biology of the cell, 5th edition by B. Alberts, A. Johnson, J. Lewis, M. Raff, K. Roberts, and P. Walter
Cell Survival and Cell Death. Edited by Eric H. Baehrecke, Douglas R. Green, Sally Kornbluth, Guy S. Salvesen. Cold Spring Harbor Laboratory Press 2013. |
| Planned Learning Activities and Teaching Methods |
- Lecture
- Discussion
- Presentation
|
| Assessment Methods and Criteria |
|
Quantity |
Percentage (%) |
| Mid-term |
1 |
30 |
| Presentation of Article |
1 |
25 |
| Total(%) |
|
55 |
| Contribution of In-term Studies to Overall Grade(%) |
|
55 |
| Contribution of Final Examination to Overall Grade(%) |
|
45 |
| Total(%) |
|
100 |
|
| ECTS Allocated Based on Student Workload |
| Activities |
Quantity |
Duration (Hour) |
Total Workload (Hour) |
| Midterm exam |
1 |
2 |
2 |
| Preparation for Quiz |
|
|
|
| Individual or group work |
|
|
|
| Preparation for Final exam |
1 |
35 |
35 |
| Course hours |
14 |
3 |
42 |
| Preparation for Midterm exam |
1 |
25 |
25 |
| Laboratory (including preparation) |
|
|
|
| Final exam |
1 |
2 |
2 |
| Homework |
|
|
|
| Article Presentation |
1 |
15 |
15 |
| Total Work Load | 121 |
| Total Work Load / 30 (h) | 4.03 |
| ECTS Credit of the Course | 4 |
|
| Language of Instruction | Turkish |
| Work Placement(s) | No |