| Course Type | Elective Course |
|---|
| Course Level | Bachelor's Degree |
|---|
| Year of Study | - |
|---|
| Semester | - |
|---|
| ECTS | 4 |
|---|
| Name of Lecturer(s) |
|
| Learning Outcomes |
At the end of this course, the students;
- Learn the description, general properties and the types of stem cells.
- Learn the markers that specify the plasticity of stem cells.
- Learn The molecular mechanisms of self-renewal, proliferation, differentiation, dedifferentiation and senescence of stem cells.
- Learn different types of stem cells; their sources, properties and applications in regenerative medicine.
- Learn different types of niches that harbor the specific types of tissue / organ stem cells
- Learn the laboratory techniques (isolation, characterization, differentiation and molecular techniques and microscopic analyses) that are used during stem cell studies.
- Know the applications of stem cells in the field of tissue engineering.
|
| Mode of Delivery | Face to face |
|---|
| Prerequisites | No |
|---|
| Recommended Optional Programme Components | None |
|---|
| Course Description | Stem Cell Biology course gives information about the molecular mechanisms that regulate the development, function and the behavior of stem cells in their microenvironment (niche), types/stem cell and about the applications of stem cells in the field of regenerative medicine and tissue engineering. It also describes the laboratory techniques that are used during stem cell research. |
|---|
| Course Contents |
| WEEK |
TOPICS |
|
1st Week |
Course introduction and discussion |
|
2nd Week |
Introduction to stem cells: general concepts, definitions |
|
3rd Week |
Molecular regulators of stem cell behavior |
|
4th Week |
Embryonic stem cells |
|
5th Week |
Induced pluripotent stem cells |
|
6th Week |
Fetal stem cells |
|
7th Week |
Scientific paper presentations |
|
8th Week |
Stem cell niches |
|
9th Week |
Adult mesenchymal and hematopoietic stem cells |
|
10th Week |
Other tissue/organ specific stem cells |
|
11th Week |
Stem cell research / laboratory techniques |
|
12th Week |
Stem cells in tissue engineering applications |
|
13th Week |
Scientific paper presentations |
|
14th Week |
Scientific paper presentations |
|
| Recommended or Required Reading | Essentials of Stem Cell Biology 3rd edition. John Gearhart, Brigid Hogan, Douglas Melton, Roger Pedersen, E. Donall Thomas, James Thomas, Sir Ian Wilmut.
Kök Hücre Biyolojisi, Türleri ve Tedavide Kullanımları (1. Basım), Alp Can, 2014. |
|---|
| Planned Learning Activities and Teaching Methods |
- Lecture
- Questions/Answers
- Presentation
- Discussion
|
|---|
| Assessment Methods and Criteria |
|
Quantity |
Percentage (%) |
| Mid-term |
1 |
30 |
| Attendance |
1 |
5 |
| Presentation of Article |
1 |
15 |
| Total(%) |
|
50 |
| Contribution of In-term Studies to Overall Grade(%) |
|
50 |
| Contribution of Final Examination to Overall Grade(%) |
|
50 |
| Total(%) |
|
100 |
|
| ECTS Allocated Based on Student Workload |
| Activities |
Quantity |
Duration (Hour) |
Total Workload (Hour) |
| Midterm exam |
1 |
2 |
2 |
| Preparation for Quiz |
|
|
|
| Individual or group work |
14 |
1 |
14 |
| Preparation for Final exam |
1 |
27 |
27 |
| Course hours |
14 |
3 |
42 |
| Preparation for Midterm exam |
1 |
25 |
25 |
| Laboratory (including preparation) |
|
|
|
| Final exam |
1 |
2 |
2 |
| Homework |
|
|
|
| Report writing |
1 |
3 |
3 |
| Article Presentation |
1 |
7 |
7 |
| Total Work Load | 122 |
| Total Work Load / 30 (h) | 4.06 |
| ECTS Credit of the Course | 4 |
|
| Language of Instruction | Turkish |
|---|
| Work Placement(s) | No |
|---|
