| Course Type | Elective Course |
| Course Level | Master's Degree With Thesis |
| Year of Study | - |
| Semester | - |
| ECTS | 6 |
| Name of Lecturer(s) |
- |
| Learning Outcomes |
At the end of this course, the students;
- Knows the general characteristics and classification of hematological malignancies,
- Knows the molecular mechanisms involved in the development of the CML,
- Knows the molecular mechanisms involved in the development of the ALL,
- Knows the molecular mechanisms involved in the development of the CLL,
- Knows the molecular mechanisms involved in the development of the AML,
- Knows the molecular mechanisms involved in the development of the myelodysplastic syndrome
- Knows the molecular genetic diagnosis and follow-up algorithms applied in hematological malignancies,
- Knows the cytogenetics and molecular cytogenetics diagnoses and follow-up algorithms applied in hematological malignancies,
|
| Mode of Delivery | Face to face |
| Prerequisites | No |
| Recommended Optional Programme Components | None |
| Course Description | This course aims to enable students to discuss the molecular genetic mechanisms of specific hematological malignancies such as CML, ALL, CLL, myelodysplastic syndromes and to get familiar with the molecular and cytogenetic methods utilized for the diagnosis of these hematological malignancies. |
| Course Contents |
| WEEK |
TOPICS |
|
1st Week |
The general characteristics and classification of hematological malignancies, |
|
2nd Week |
The molecular mechanisms involved in the development of the CML, |
|
3rd Week |
The molecular mechanisms involved in the development of the ALL, |
|
4th Week |
The molecular mechanisms involved in the development of the CLL, |
|
5th Week |
The molecular mechanisms involved in the development of the AML, |
|
6th Week |
The molecular mechanisms involved in the development of the myelodysplastic syndrome |
|
7th Week |
The molecular genetic diagnosis and follow-up algorithms applied in hematological malignancies, |
|
8th Week |
The cytogenetics and molecular cytogenetics diagnoses and follow-up algorithms applied in hematological malignancies, |
|
9th Week |
|
|
10th Week |
|
|
| Recommended or Required Reading | Thompson & Thompson Genetics in Medicine (7th Edition), Robert Nussbaum, Saunders, 2007. |
| Planned Learning Activities and Teaching Methods |
- Lecture
- Discussion
- Questions/Answers
- Presentation
|
| Assessment Methods and Criteria |
|
Quantity |
Percentage (%) |
| Mid-term |
1 |
50 |
| Total(%) |
|
50 |
| Contribution of In-term Studies to Overall Grade(%) |
|
50 |
| Contribution of Final Examination to Overall Grade(%) |
|
50 |
| Total(%) |
|
100 |
|
| ECTS Allocated Based on Student Workload |
| Activities |
Quantity |
Duration (Hour) |
Total Workload (Hour) |
| Midterm exam |
1 |
2 |
2 |
| Preparation for Quiz |
1 |
5 |
5 |
| Individual or group work |
14 |
2 |
28 |
| Preparation for Final exam |
1 |
20 |
20 |
| Course hours |
14 |
3 |
42 |
| Preparation for Midterm exam |
1 |
11 |
11 |
| Laboratory (including preparation) |
|
|
|
| Final exam |
1 |
2 |
2 |
| Homework |
2 |
35 |
70 |
| Total Work Load | 180 |
| Total Work Load / 30 (h) | 6 |
| ECTS Credit of the Course | 6 |
|
| Language of Instruction | Turkish |
| Work Placement(s) | No |