Information Package

Master's of Medical Genetics with Thesis

GEN514

GENETICS AND DIAGNOSIS OF HEMATOLOGICAL MALIGNANCIES

Course Code
GEN514
Semester
-
Theory+Practice
3 + 0
ECTS
6
Course TypeElective Course
Course LevelMaster's Degree With Thesis
Year of Study-
Semester-
ECTS6
Name of Lecturer(s) -
Learning Outcomes

At the end of this course, the students;

  1. Knows the general characteristics and classification of hematological malignancies,
  2. Knows the molecular mechanisms involved in the development of the CML,
  3. Knows the molecular mechanisms involved in the development of the ALL,
  4. Knows the molecular mechanisms involved in the development of the CLL,
  5. Knows the molecular mechanisms involved in the development of the AML,
  6. Knows the molecular mechanisms involved in the development of the myelodysplastic syndrome
  7. Knows the molecular genetic diagnosis and follow-up algorithms applied in hematological malignancies,
  8. Knows the cytogenetics and molecular cytogenetics diagnoses and follow-up algorithms applied in hematological malignancies,
Mode of DeliveryFace to face
PrerequisitesNo
Recommended Optional Programme ComponentsNone
Course DescriptionThis course aims to enable students to discuss the molecular genetic mechanisms of specific hematological malignancies such as CML, ALL, CLL, myelodysplastic syndromes and to get familiar with the molecular and cytogenetic methods utilized for the diagnosis of these hematological malignancies.
Course Contents
WEEK TOPICS
1st Week The general characteristics and classification of hematological malignancies,
2nd Week The molecular mechanisms involved in the development of the CML,
3rd Week The molecular mechanisms involved in the development of the ALL,
4th Week The molecular mechanisms involved in the development of the CLL,
5th Week The molecular mechanisms involved in the development of the AML,
6th Week The molecular mechanisms involved in the development of the myelodysplastic syndrome
7th Week The molecular genetic diagnosis and follow-up algorithms applied in hematological malignancies,
8th Week The cytogenetics and molecular cytogenetics diagnoses and follow-up algorithms applied in hematological malignancies,
9th Week
10th Week
Recommended or Required ReadingThompson & Thompson Genetics in Medicine (7th Edition), Robert Nussbaum, Saunders, 2007.
Planned Learning Activities and Teaching Methods
  • Lecture
  • Discussion
  • Questions/Answers
  • Presentation
Assessment Methods and Criteria
Quantity Percentage (%)
Mid-term 1 50
Total(%) 50
Contribution of In-term Studies to Overall Grade(%) 50
Contribution of Final Examination to Overall Grade(%) 50
Total(%) 100
ECTS Allocated Based on Student Workload
Activities Quantity Duration (Hour) Total Workload (Hour)
Midterm exam 1 2 2
Preparation for Quiz 1 5 5
Individual or group work 14 2 28
Preparation for Final exam 1 20 20
Course hours 14 3 42
Preparation for Midterm exam 1 11 11
Laboratory (including preparation)
Final exam 1 2 2
Homework 2 35 70
Total Work Load180
Total Work Load / 30 (h)6
ECTS Credit of the Course6
Language of InstructionTurkish
Work Placement(s)No
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