Information Package
baskent.edu.tr

Master's of Pharmacology with Thesis

PHAR513

BASIC PHARMACOLOGY OF ENDOTHELIUM DERIVED SUBSTANCES

Course Code
PHAR513
Semester
-
Theory+Practice
2 + 0
ECTS
3
Course TypeElective Course
Course LevelMaster's Degree With Thesis
Year of Study-
Semester-
ECTS3
Name of Lecturer(s) -
Learning Outcomes

At the end of this course, the students;

  1. List the endothelium-derived bioactive substances
  2. Tell their effects
  3. Explain their mechanisms of actions
  4. Explain the current and possible pharmacological uses of these substances
Mode of DeliveryFace to face
PrerequisitesNo
Recommended Optional Programme ComponentsNone
Course Description
Course Contents
WEEK TOPICS
1st Week Endothelium: structure, function and physiological importance,
2nd Week Prostanoids,
3rd Week Thorombotical factors: tPA, thrombomoduline, thromboplastine, PAF
4th Week Endothelins: synthesis and functional importance 1
5th Week Endothelins: synthesis and functional importance 2
6th Week Angiothensins: synthesis and functional importance 1
7th Week Angiothensins: synthesis and functional importance 2
8th Week Mid-term
9th Week Nitric oxide (I): synthesis and functional importance
10th Week Nitric oxide (II): physiological importance and targets
11th Week Nitric oxide (III): cardiovascular system
12th Week Nitric oxide (IV): central nervous system
13th Week Others: EDHF etc.
14th Week General review
Recommended or Required Reading- Rasyonel Tedavi Yönünden Tıbbi Farmakoloji, Prof. Dr. S. Oğuz Kayaalp, 12. baskı, Pelikan Yay. Ltd. Şti., Ankara, 2009 (ISBN: 978-9944-119-73-3).
- Goodman & Gilman's The Pharmacological Basis of Therapeutics, J.G. Hardman ve L.E. Limbird (editörler), onbirinci baskı, McGraw-Hill, New York, 2006.
- Goodman & Gilman's Manual of Pharmacology and Therapeutics, L.L. Brunton, K.L. Parker (editörler), onbirinci baskı, McGraw-Hill, New York, 2008.
- Basic & Clinical Pharmacology, B.G. Katzung (editör), dokuzuncu baskı, Appleton & Lange, Stamford, 2004.
- Pharmacology, H.P. Rang, M.M. Dale, J. M. Ritter, R. J. Flower, G. Henderson (editörler), yedinci baskı, Churchill Livingstone, Elsevier, İspanya, 2011.
- Melmon & Morelli's Clinical Pharmacology, S.G. Carruthers, B.B. Hoffman, K.L. Melmon, D.W. Nierenberg (editörler), dördüncü baskı, McGraw-Hill, New York, 2000.
- Clinical Pharmacology, P.N. Bennett, M. J. Brown (editörler), dokuzuncu baskı, Churchill Livingstone, Elsevier, İspanya, 2003.
- Pharmacology, G. M. Brenner, C. W. Stevens (editörler), üçüncü baskı, Saunders Elsevier, Çin, 2010.
- Avery's Drug Treatment, T.M. Speight ve N.H.G. Holford (editörler), dördüncü baskı, Adis International, Auckland, 1997.
- Drug Interactions Handbook, K.A. Bachman (editör), Lexi-Comp Inc., Hudson-Ohio, 2003.
- BNF/TİK-5 Türkiye İlaç Kılavuzu-2007 Formüleri, S.Oğuz Kayaalp (ed.), Turgut Yayıncılık ve Ticaret A.Ş., İstanbul, 2007.
- Netter's Illustrated Pharmacology, R.B. Baffa, Rawls S.M., Beyzarov E.P. (editörler), Icon Learning Systems, A.B.D., 2005.
- Pharmacology, G.M. Brenner ve C. W. Stevens (editörler), üçüncü baskı, Saunders Elsevier, Philadelphia, A.B.D., 2010.
Planned Learning Activities and Teaching Methods
  • Lecture
  • Discussion
  • Questions/Answers
  • Presentation
Assessment Methods and Criteria
Quantity Percentage (%)
Mid-term 1 25
Total(%) 25
Contribution of In-term Studies to Overall Grade(%) 25
Contribution of Final Examination to Overall Grade(%) 75
Total(%) 100
Language of InstructionTurkish
Work Placement(s)No

Programme Qualifications / Learning Outcomes

LO1 LO2 LO3 LO4
K1 X
K2 X X X X
K3
K4
K5
K6
K7
K8
K9 X X X X
K10