Information Package

Master's of Pharmacology with Thesis

PHAR503

BASIC PHARMACOLOGY OF NEUROTRANSMITTERS

Course Code
PHAR503
Semester
Second Term (Spring)
Theory+Practice
3 + 0
ECTS
5
Course TypeCompulsory Course
Course LevelMaster's Degree With Thesis
Year of Study1
SemesterSecond Term (Spring)
ECTS5
Name of Lecturer(s) -
Learning Outcomes

At the end of this course, the students;

  1. List major neurotransmitters
  2. Explain the terms synapse and nerve-muscle junction
  3. Explain the major steps of neurotransmission process
  4. Explain the basic mechanisms mediating the effects of neurotransmitters
Mode of DeliveryFace to face
PrerequisitesNo
Recommended Optional Programme ComponentsNone
Course Description
Course Contents
WEEK TOPICS
1st Week Definition of the neurotransmission concept
2nd Week Neurotransmitters and neuromodulators: Classification
3rd Week Neurotransmitters and neuromodulators: biosyntheses and release
4th Week Basic action mechanisms of neurotransmitters, second messengers
5th Week Drugs acting on neurotransmitters and intercellular interaction
6th Week Synapses: anatomicaphysiology and basic pharmacological principles of synaptic transmission
7th Week Mid-term
8th Week Synaptic plastisisite, LTP, LTD
9th Week Nerve-muscle junction: anatomicaphysiology and basic pharmacology
10th Week Basic principles of central nerve system neurotransmission
11th Week Basic principles of ANS neurotransmission
12th Week Basic principles of peripheral nerve system neurotransmission
13th Week Basic principles of central neuroendocrine system neurotransmission
14th Week Discussion
Recommended or Required Reading- Rasyonel Tedavi Yönünden Tıbbi Farmakoloji, Prof. Dr. S. Oğuz Kayaalp, 12. baskı, Pelikan Yay. Ltd. Şti., Ankara, 2009 (ISBN: 978-9944-119-73-3).
- Goodman & Gilman's The Pharmacological Basis of Therapeutics, J.G. Hardman ve L.E. Limbird (editörler), onbirinci baskı, McGraw-Hill, New York, 2006.
- Goodman & Gilman's Manual of Pharmacology and Therapeutics, L.L. Brunton, K.L. Parker (editörler), onbirinci baskı, McGraw-Hill, New York, 2008.
- Basic & Clinical Pharmacology, B.G. Katzung (editör), dokuzuncu baskı, Appleton & Lange, Stamford, 2004.
- Pharmacology, H.P. Rang, M.M. Dale, J. M. Ritter, R. J. Flower, G. Henderson (editörler), yedinci baskı, Churchill Livingstone, Elsevier, İspanya, 2011.
- Melmon & Morelli's Clinical Pharmacology, S.G. Carruthers, B.B. Hoffman, K.L. Melmon, D.W. Nierenberg (editörler), dördüncü baskı, McGraw-Hill, New York, 2000.
- Clinical Pharmacology, P.N. Bennett, M. J. Brown (editörler), dokuzuncu baskı, Churchill Livingstone, Elsevier, İspanya, 2003.
- Pharmacology, G. M. Brenner, C. W. Stevens (editörler), üçüncü baskı, Saunders Elsevier, Çin, 2010.
- Avery's Drug Treatment, T.M. Speight ve N.H.G. Holford (editörler), dördüncü baskı, Adis International, Auckland, 1997.
- Drug Interactions Handbook, K.A. Bachman (editör), Lexi-Comp Inc., Hudson-Ohio, 2003.
- BNF/TİK-5 Türkiye İlaç Kılavuzu-2007 Formüleri, S.Oğuz Kayaalp (ed.), Turgut Yayıncılık ve Ticaret A.Ş., İstanbul, 2007.
- Netter's Illustrated Pharmacology, R.B. Baffa, Rawls S.M., Beyzarov E.P. (editörler), Icon Learning Systems, A.B.D., 2005.
- Pharmacology, G.M. Brenner ve C. W. Stevens (editörler), üçüncü baskı, Saunders Elsevier, Philadelphia, A.B.D., 2010.
Planned Learning Activities and Teaching Methods
  • Lecture
  • Discussion
  • Questions/Answers
  • Presentation
Assessment Methods and Criteria
Quantity Percentage (%)
Mid-term 1 25
Total(%) 25
Contribution of In-term Studies to Overall Grade(%) 25
Contribution of Final Examination to Overall Grade(%) 75
Total(%) 100
Language of InstructionTurkish
Work Placement(s)No
LO1 LO2 LO3 LO4
K1 X
K2 X X X X
K3
K4
K5
K6
K7
K8
K9 X X X X
K10