INTERACTIONS AND TOXICOLOGICAL RESULTS

ECF542

Course Code: ECF542
Semester: -
Theory+Practice: 2 + 0
ECTS: 5

Course Type

Elective Course

Course Level

Master's Degree Without Thesis

Year of Study

Semester

ECTS

Name of Lecturer(s)

Professor Hilal Özgüneş

Learning Outcomes

At the end of this course, the students;

Learn drug-drug interactions
Learn drug-food interactions
Learn drug-alcohol interactions
Learn drug-herbal product interactions

Mode of Delivery

Face to face

Prerequisites

Recommended Optional Programme Components

None

Course Description

The course covers following topics:,Drug-drug,Drug-food,Drug-alcohol, Drug-herbalproduct interactions and toxicological consequences of these interactions.

Course Contents

WEEK	TOPICS
1^st Week	Introduction to type of interactions,mechanisms of interactions and toxicological consequences of interactions
2^nd Week	Pharmacodynamic interactions:Synergism
3^rd Week	Pharmacodynamic interactions:Antagonism
4^th Week	Pharmacokinetic interactions involve absorption and distribution
5^th Week	Pharmacokinetic interactions involve metabolism and excretion
6^th Week	Important drug-drug interactions
7^th Week	Midterm examination
8^th Week	Important drug-drug interactions
9^th Week	Important drug-drug interactions
10^th Week	Drug-food interactions
11^th Week	Drug-alcohol interactions
12^th Week	Drug-herbal product interactions
13^th Week	Discussion
14^th Week	Final exam

Recommended or Required Reading

1. Casarett & Doull's Toxicology, The Basic Science of Poisons,Eighth edition,Mc graw-Hill Companies,Medical editör:C.D.Klaassen,2019.
2. Ellenhorn, M.J., "Medical Toxicology", Williams & Wilkins, Maryland, 1997. 3.S.Sabuncuoğlu,H.Özgüneş:Etkileşmeler ve Toksikolojik Sonuçları,Toksikoloji,Hacettepe Üniversitesi Yayınları,299-327,2020.
3. S.Oğuz Kayaalp:.Rasyonel Tedavi Yönünden Tıbbi Farmakoloji,4.baskı,1987.
4. Mozayani A., Rayman L.P.,Handbook of Drug Interactions, Humana Press, New Jersey, 2012.

Planned Learning Activities and Teaching Methods

Lecture
Discussion

Assessment Methods and Criteria

	Quantity	Percentage (%)
Mid-term	1	15
Assignment	3	15
Other	1	10
Total(%)		40
Contribution of In-term Studies to Overall Grade(%)		40
Contribution of Final Examination to Overall Grade(%)		60
Total(%)		100

ECTS Allocated Based on Student Workload

Activities	Quantity	Duration (Hour)	Total Workload (Hour)
Midterm exam	1	1	1
Preparation for Quiz	0	0	0
Individual or group work	14	2	28
Preparation for Final exam	1	20	20
Course hours	14	2	28
Preparation for Midterm exam	1	15	15
Laboratory (including preparation)	0	0	0
Final exam	1	2	2
Homework	3	10	30
Presentation (including preperation)	1	10	10
Literature review	4	4	16
Total Work Load			150
Total Work Load / 30 (h)			5
ECTS Credit of the Course			5

Language of Instruction

Turkish

Work Placement(s)

Programme Qualifications / Learning Outcomes

	LO1	LO2	LO3	LO4
K1
K2
K3
K4
K5
K6	X	X	X	X
K7
K8	X	X	X	X