Information Package

Program of Pharmacy

ECZ452

SEPARATION AND CHROMATOGRAPHIC METHODS IN DRUG ANALYSIS

Course Code
ECZ452
Semester
-
Theory+Practice
2 + 0
ECTS
2
Course TypeElective Course
Course LevelBachelor's Degree
Year of Study-
Semester-
ECTS2
Name of Lecturer(s)
Learning Outcomes

At the end of this course, the students;

  1. Knows Classification of Qualitative and Quantitative Analysis Methods. Knows the theoretical information that is important in the selection of the qualitative and quantitative Analysis Method of drugs from biological materials. Knows where the analyzes are used in the field of pharmacy and health.
  2. Knows the biological materials and the preparation of drugs from biological materials for analysis.
  3. Knows introduction to chromatography, introduction and classification of basic concepts.
  4. Mathematical parameters in chromatography and are evaluated.
  5. He / she can choose an appropriate chromatographic method in drug analysis from biological materials and know its application.
  6. Knows the introduction and classification of spectroscopic methods and theoretical foundations of spectrophotometric methods.
  7. Mathematical parameters in spectrophotometry and their evaluation Knows the appropriate spectroscopic method selection and application in drug analysis among biological materials.
  8. Introduction to electrochemical methods and their classification, introduction of basic concepts of Electrochemical Methods.Mathematical parameters in electrochemistry and their evaluation.Knows the selection and application of the appropriate electrochemical method in drug analysis from biological materials.
  9. Can use the information learned in this course in the business areas (industry) he / she works after graduation.
Mode of DeliveryFace to face
PrerequisitesNo
Recommended Optional Programme ComponentsNone
Course DescriptionTheoretical bases and applications of qualitative and quantitative analysis of drugs from biological materials.
Course Contents
WEEK TOPICS
1st Week Theoretical information about separation principles and separation methods
2nd Week Liquid - solid consumption
3rd Week Liquid - liquid consumption
4th Week Definition, classification and theory of chromatography. Concepts, meanings and formulas in chromatography
5th Week Planar chromatography (Thin layer and paper chromatography)
6th Week Column chromatography
7th Week Midterm exam
8th Week Ion exchange chromatograph
9th Week Gel chromatography and gas chromatography
10th Week Gas chromatography
11th Week Capillary electrophoresi
12th Week High pressure liquid chromatography (HPLC)
13th Week High pressure liquid chromatography (HPLC)
14th Week Combined methods
Recommended or Required Reading1. A. Yıldız, Ö. Genç, S. Bektaş, Enstrümantal Analiz Yöntemleri, İkinci Baskı, Hacettepe Üniversitesi Yayınları, 1997.
2. D.A. Skoog, F.J. Holler, T.A. Nieman, Enstrümental Analiz İlkeleri, Bilim Yayıncılık, 2007.
3. H.H. Willard, L.L. Merritt, J.A. Dean, F.A. Settle, Instrumental Methods of Analysis, Sixth Edition, Litton Educational, USA, 1981.
4. D.A. Skoog, F.J. Holler, S.R. Crouch, Principles Instrumental Analysis, Sixth Edition, Brooks Cole, USA, 2006.
5. P. A. Sewell, B. Clarke, Chromatographic Separation, John Wiley & Sons, 1987.
6. OTHER RELATED RECENT GUIDES, PAPERS AND BOOKS
Planned Learning Activities and Teaching Methods
  • Lecture
  • Discussion
  • Problem Solving
Assessment Methods and Criteria
Quantity Percentage (%)
Mid-term 1 35
Assignment 1 15
Total(%) 50
Contribution of In-term Studies to Overall Grade(%) 50
Contribution of Final Examination to Overall Grade(%) 50
Total(%) 100
ECTS Allocated Based on Student Workload
Activities Quantity Duration (Hour) Total Workload (Hour)
Midterm exam 1 1 1
Preparation for Quiz 0 0 0
Individual or group work 14 1 14
Preparation for Final exam 1 10 10
Course hours 14 2 28
Preparation for Midterm exam 1 5 5
Laboratory (including preparation) 0 0 0
Final exam 1 2 2
Homework 0 0 0
Total Work Load60
Total Work Load / 30 (h)2
ECTS Credit of the Course2
Language of InstructionTurkish
Work Placement(s)No
LO1 LO2 LO3 LO4 LO5 LO6 LO7 LO8 LO9
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K3 X X X X X X X X X
K4 X X X X X X X X X
K5 X X X X X X X X X
K6
K7
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K9 X X X X X X X X X
K10
K11
K12
K13
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K16 X X