STRUCTURE ELUCIDATION IN DRUGS

ECZ438

Course Code: ECZ438
Semester: -
Theory+Practice: 2 + 0
ECTS: 2

Course Type

Elective Course

Course Level

Bachelor's Degree

Year of Study

Semester

ECTS

Name of Lecturer(s)

Professor Osman Cihat Şafak

Learning Outcomes

At the end of this course, the students;

Learns the basic spectral methods used in the structure of organic compounds.
Evaluates the spectra obtained from these methods

Mode of Delivery

Face to face

Prerequisites

Recommended Optional Programme Components

None

Course Description

Structure determination of drug active ingredients. Introduction to spectroscopy and basic principles. Ultraviyolet and visible spectroscopy. Infrared spectroscopy, Nuclear magnetic resonance spectroscopy, Mass spectroscopy.

Course Contents

WEEK	TOPICS
1^st Week	Structure determination of drug active ingredients
2^nd Week	Introduction to spectroscopy and basic principles
3^rd Week	Introduction to spectroscopy and basic principles
4^th Week	Ultraviyolet and visible spectroscopy
5^th Week	Infrared spectroscopy
6^th Week	Infrared spectroscopy
7^th Week	Midterm exam
8^th Week	Nuclear magnetic resonance spectroscopy
9^th Week	Nuclear magnetic resonance spectroscopy
10^th Week	Nuclear magnetic resonance spectroscopy
11^th Week	Nuclear magnetic resonance spectroscopy
12^th Week	Nuclear magnetic resonance spectroscopy
13^th Week	Mass spectroscopy
14^th Week	Mass spectroscopy

Recommended or Required Reading

1. Silverstein, R.M., Webster F. X., `Spectrometric Identification of Organic Compounds?, New York, 2005.
2. Ergenç, N., `İlaçların Tanınması ve Kalitatif Tayini? İstanbul, 1989.
3. Skoog, D.A., West D.M., `Principle of Instrumental Analysis? Philadelphia, 1980.
4. Willard H. H., Merritt L. L., Dean J. A., Seettle, F. A., `Instrumental Method of Analysis?, Belmont California (1988).
5. Pouchert, C.J., Behnke, J., The Aldrich Library of 13C and 1H FT-NMR Spectra, Aldrich Chemical, Milwaukee (1992)
6. Balcı M., `Nucleer Magnetic Rezonans Spektroskopisi?, Ankara 2000.
7. Williams, D.H., Fleming, I., Spectroscopic Methods in Organic Chemistry, London (1995).
8. Crews P., Rodriguez J, Jaspars M., Organic Structure Analysis, New York (1998).
9. Shriner R L., Hermann C., Morrill TC., Curtin DY., Fuson RC, The Systematic Identification of Organic Compounds (1999).
10. Hesse, M., Meier, H., Zeeh, B., Spectroscopic Methods in Organic Chemistry, Thieme, Stuttgart (2008).

Planned Learning Activities and Teaching Methods

Lecture
Questions/Answers
Problem Solving
Discussion

Assessment Methods and Criteria

	Quantity	Percentage (%)
Mid-term	1	40
Total(%)		40
Contribution of In-term Studies to Overall Grade(%)		40
Contribution of Final Examination to Overall Grade(%)		60
Total(%)		100

ECTS Allocated Based on Student Workload

Activities	Quantity	Duration (Hour)	Total Workload (Hour)
Midterm exam	1	1	1
Preparation for Quiz	0	0	0
Individual or group work	14	1	14
Preparation for Final exam	1	10	10
Course hours	14	2	28
Preparation for Midterm exam	1	5	5
Laboratory (including preparation)	0	0	0
Final exam	1	2	2
Homework	0	0	0
Total Work Load			60
Total Work Load / 30 (h)			2
ECTS Credit of the Course			2

Language of Instruction

Turkish

Work Placement(s)

Programme Qualifications / Learning Outcomes

	LO1	LO2
K1
K2
K3
K4
K5	X	X
K6
K7
K8
K9	X	X
K10
K11
K12
K13
K14
K15
K16