Information Package
baskent.edu.tr

Program of Pharmacy

ECZ380

PHARMACEUTICAL TOXICOLOGY I

Course Code
ECZ380
Semester
Sixth Term (Spring)
Theory+Practice
2 + 0
ECTS
3
Course TypeCompulsory Course
Course LevelBachelor's Degree
Year of Study3
SemesterSixth Term (Spring)
ECTS3
Name of Lecturer(s)
Learning Outcomes

At the end of this course, the students;

  1. Absorption ,distribution,biotransformation and excretion of toxicants
  2. Mechanisms of toxicity and factors affecting toxicity
  3. Carcinogenesis and teratogenesis
  4. Drug usage in pregnancy and lactation
  5. Drug-drug interactios,drug-food interactions and drug-alcohol interactions
Mode of DeliveryFace to face
PrerequisitesNo
Recommended Optional Programme ComponentsNone
Course DescriptionThe course covers following topics:General principles of toxicology,toxicocinetic,,mechanisms of toxic effects,factors affecting toxicity, mutagenesis,carcinogenesis,teratogenesis,drug-drug,drug-food,drug-alcohol interactions,management of poisoning.
Course Contents
WEEK TOPICS
1st Week General concepts of toxicologyAbsorption ,distribution, and excretion of toxicants
2nd Week Toxicity tests
3rd Week Toxicokinetics
4th Week Toxicokinetics
5th Week Mutagenesis
6th Week Management of acute poisoning
7th Week Midterm examination
8th Week Teratogenesis
9th Week The toxicological importance of genetic polymorphism
10th Week Genotoxicity
11th Week Teratogenesis
12th Week Immunotoxicity
13th Week Drug-drug, drug-food, drug-alcohol, drug-herbal product interactions
14th Week General examination
Recommended or Required Reading1. Klaassen, C.D., Watkins J.W., "Casarett & Doull?s Toxicology, The McGraw Hill Companies, 2010.
2. Ellenhorn, M.J., "Medical Toxicology", Williams & Wilkins, Maryland, 1997.
3. Hayes, A.W., "Principles and Methods of Toxicology", Taylor & Francis, Philadelphia, 2001.
4. Frank C.Lu ,Sam Kacew,LU?s Basic Toxicology, Sixth edition,2012.
5.S.Oğuz Kayaalp:Rasyonel Tedavi yönünden Tıbbi Farmakoloji,4.baskı,1987.
Planned Learning Activities and Teaching Methods
  • Lecture
  • Discussion
  • Questions/Answers
  • Presentation
Assessment Methods and Criteria
Quantity Percentage (%)
Mid-term 1 40
Total(%) 40
Contribution of In-term Studies to Overall Grade(%) 40
Contribution of Final Examination to Overall Grade(%) 60
Total(%) 100
ECTS Allocated Based on Student Workload
Activities Quantity Duration (Hour) Total Workload (Hour)
Midterm exam 1 1 1
Preparation for Quiz 0 0 0
Individual or group work 14 2 28
Preparation for Final exam 1 20 20
Course hours 14 2 28
Preparation for Midterm exam 1 10 10
Laboratory (including preparation) 0 0 0
Final exam 1 2 2
Homework 0 0 0
Total Work Load89
Total Work Load / 30 (h)2.96
ECTS Credit of the Course3
Language of InstructionTurkish
Work Placement(s)No

Programme Qualifications / Learning Outcomes

LO1 LO2 LO3 LO4 LO5
K1
K2
K3
K4
K5
K6
K7
K8
K9
K10
K11
K12
K13
K14
K15
K16