The principles and application of all kinds of chromatography technics,
Separation of solid-solid and liquid-liquid mixtures,
Some physical properties such as molecular weight, density, melting and boiling points, refractive index, spesific optical rotation and their determination methods.
Mode of Delivery
Face to face
Prerequisites
No
Recommended Optional Programme Components
None
Course Description
Chromatographic technics, separation of liquid-liquid and solid-solid mixtures. Determination of density, boiling point, melting point, refractive index and spesific rotation. Pharmacopea analysis. The principles of various quantitative analyses used in drug analysis (titrimetric, electroanalytic, optical and spectral). Application of quantitative methods to raw materials and pharmaceutical products.
Course Contents
WEEK
TOPICS
1st Week
Theoretical concepts
2nd Week
Theoretical concepts
3rd Week
Paper chromatography
4th Week
Column chromatography
5th Week
Separation of solid-solid mixtures
6th Week
Separation of liquid-liquid mixtures
7th Week
Midterm-exam
8th Week
Determination of density
9th Week
Determination of boiling point
10th Week
Determination of melting point
11th Week
Determination of refractive index
12th Week
Determination of spesific rotation
13th Week
Compendial analysis
14th Week
Compendial analysis
Recommended or Required Reading
1. Stahl, E., 'Thin-layer Chromatography', 2nd ed, Springer-Verlag, New York, 1969.
2. Miller, J.A., Neuzil, E.F., ?Modern Experimental Organic Chemistry?, D.C. Heath and Company, Lexington, Massachusetts, 1982.
Planned Learning Activities and Teaching Methods
Lecture
Discussion
Questions/Answers
Assessment Methods and Criteria
Quantity
Percentage (%)
Mid-term
1
20
Practice
10
30
Total(%)
50
Contribution of In-term Studies to Overall Grade(%)
50
Contribution of Final Examination to Overall Grade(%)
