PHARMACEUTICAL CHEMISTRY I

ECZ331

Course Code: ECZ331
Semester: Fifth Term (Fall)
Theory+Practice: 3 + 0
ECTS: 4

Course Type

Compulsory Course

Course Level

Bachelor's Degree

Year of Study

Semester

Fifth Term (Fall)

ECTS

Name of Lecturer(s)

Professor Selma Saraç Tarhan

Learning Outcomes

At the end of this course, the students;

Drug design and its steps,
Methods ort he optimization of lead compound by molecular modification techniques,
The effect of physicochemical properties of drugs and drug-receptor interactions,
Biotransformation,
General anesthetics, sedatives and hypnotics, tranquilizers, neuroleptics, anticonvulsant drugs, CNS-acting muscle relaxant drugs, and analgesic drugs.

Mode of Delivery

Face to face

Prerequisites

Recommended Optional Programme Components

None

Course Description

Introduction to pharmaceutical chemistry and basic concepts, biotransformations, central nervous system drugs, general anesthetics, sedatif-hypnotices, tranquilizers, neuroleptics, central acting spasmolytics, anticonvulsants, antidepressants, local anesthetics, non-steroidal antiinflammatory drugs, narcotic analgesics.

Course Contents

WEEK	TOPICS
1^st Week	Introduction to pharmaceutical chemistry and basic concepts
2^nd Week	Introduction to pharmaceutical chemistry and basic concepts
3^rd Week	Introduction to pharmaceutical chemistry and basic concepts
4^th Week	Drug biotransformation
5^th Week	Central System drugs, general anaesthetics
6^th Week	Sedatives and hypnotics
7^th Week	Midterm-exam
8^th Week	Tranquülizers
9^th Week	Neuroleptics / Local anaesthetic
10^th Week	Antidepressants, antiepileptics / analeptics
11^th Week	Anti-Alzheimer drugs, antiparkinsons and central acting spasmolytics
12^th Week	Narcotic analgesics
13^th Week	Analgesics
14^th Week	Analgesics

Recommended or Required Reading

1. Akgün, H., Balkan, A., Bilgin, A.A., Çalış, Ü., Dalkara, S., Erdoğan, H., Erol Demir, D., Ertan, M., Gökhan, N., Özkanlı, F., Palaska, E., Saraç, S. Şafak, C., Tozkoparan. B.: Farmasötik Kimya, Ankara, 2019.
2. Foye?s Principles of Medicinal Chemistry, Lemke and Williams, 7th ed, Lippincott Williams &Wilkins, Kluwers Philadelphia, 2013.
3. Thomas, G., Fundamentals of Medicinal Chemistry, Wiley, 2003.
4. Patrick, G.L., An Introduction to Medicinal Chemistry, Oxford University Press, Oxford, 1999.

Planned Learning Activities and Teaching Methods

Lecture
Questions/Answers
Discussion

Assessment Methods and Criteria

	Quantity	Percentage (%)
Mid-term	1	40
Total(%)		40
Contribution of In-term Studies to Overall Grade(%)		40
Contribution of Final Examination to Overall Grade(%)		60
Total(%)		100

ECTS Allocated Based on Student Workload

Activities	Quantity	Duration (Hour)	Total Workload (Hour)
Midterm exam	1	1	1
Preparation for Quiz	0	0	0
Individual or group work	14	3	42
Preparation for Final exam	1	20	20
Course hours	14	3	42
Preparation for Midterm exam	1	12	12
Laboratory (including preparation)	0	0	0
Final exam	1	2	2
Homework	0	0	0
Total Work Load			119
Total Work Load / 30 (h)			3.96
ECTS Credit of the Course			4

Language of Instruction

Turkish

Work Placement(s)

Programme Qualifications / Learning Outcomes

	LO1	LO2	LO3	LO4	LO5
K1
K2
K3		X	X	X
K4
K5	X	X	X	X	X
K6
K7
K8
K9
K10			X	X
K11
K12
K13
K14
K15
K16

	LO1	LO2	LO3	LO4	LO5
K1
K2
K3		X	X	X
K4
K5	X	X	X	X	X
K6
K7
K8
K9
K10			X	X
K11
K12
K13
K14
K15
K16

	LO1	LO2	LO3	LO4	LO5
K1
K2
K3		X	X	X
K4
K5	X	X	X	X	X
K6
K7
K8
K9
K10			X	X
K11
K12
K13
K14
K15
K16

	LO1	LO2	LO3	LO4	LO5
K1
K2
K3		X	X	X
K4
K5	X	X	X	X	X
K6
K7
K8
K9
K10			X	X
K11
K12
K13
K14
K15
K16