Information Package
baskent.edu.tr

Program of Medicine (Turkish)

EMF248

BLOOD AND LYMPH SYSTEM

Course Code
EMF248
Semester
Phase II
Theory+Practice
0 + 70
ECTS
4.5
Course TypeCompulsory Course
Course LevelMedical Diploma
Year of Study16
SemesterPhase II
ECTS4.5
Name of Lecturer(s)
Learning Outcomes

At the end of this course, the students;

  1. To be able to name and describe the structure and function of each formed element in blood
  2. To be able to name hematopoietic stem cells and describe the formation of blood cells in the bone marrow.
  3. To be able to describe the sequence of events of clot formation, including the roles of the platelets and various plasma proteins
  4. To be able to identify the formed elements in blood smear
  5. To be able to tell the functions of the lymphoid system at cell, tissue and organ levels
  6. To be able to distinguish between cell-mediated and humoral immunity
  7. To be able to describe lymphocyte differentiation, activation, hypersensitivity reactions
  8. To be able to locate lymphatic vessels in the body
  9. To be able to explain the genetic mechanisms related to immune system
Mode of DeliveryFace to face
PrerequisitesNo
Recommended Optional Programme ComponentsThe entire curriculum of the academic year
Course DescriptionThis course is carried out with the co-operation of Anatomy, Physiology, Histology & Embryology, Immunology, Medical Biochemistry and Medical Genetics Departments. The name, structure and function of each formed element in blood are described. Hematopoietic stem cells and formation of blood cells in the bone marrow is described. The sequence of events of clot formation, including the roles of the platelets and various plasma proteins are explained. Blood groups, blood transfusion, and related concepts are described. The names, locations and functions of the lymphoid cells, tissues and organs composing lymphoid system are explained. Antigen, antibody, complement, MHC molecules, cytokines, lymphocyte differentiation, cellular/humoral immunity and hypersensitivity reactions are described. The information about vaccines and serological tests is given. In accordance with lectures, practical work in the laboratory environment were applied to reinforce theoretical knowledge.
Course Contents Anatomy, Physiology, Histology & Embryology, Immunology, Medical Biochemistry and Medical Genetics Departments contributes to this course. It covers basic concepts, cells/structures and mechanisms related to lymphatic system and blood.
Recommended or Required ReadingANATOMY
1. Sancak B, Cumhur M (2008) Fonksiyonel Anatomi: Baş-Boyun ve İç Organlar, Ankara: Metu Press
2. Ozan H (2004) Anatomi, Ankara Nobel
3. Snell RS (1998) Clinical Anatomy for Medical Students, Washington: Lıppıncot-Wıllıams & Wılkıns
4. Moore KL (1999) Clinically Oriented Anatomy, Baltimore Wıllıams&Wılkıns Fourth Edition
5. Snell RS (1997) Clinical Neuroanatomy for Medical Students, Phladelphia Lıppıncott ? Raven

Atlasses
1. Netter FH (2008) Atlas of Human Anatomy ÇeviriEditörü: Prof. Dr. Meserret Cumhur Nobel Tıp Kitabevleri Ankara
2. Sobotta Anatomi Atlası (2006) A.Elhan Beta Basın Evi İnsan Anatomisi Fotoğraflı Disseksiyon Atlası Türkçe Baskı Rohen / Yokochi / Lütjen ? Drecoll Çeviri: Salih Murat Akkın
3. Grant?s Eleventh Edition (2005) Lippincott Williams &Wilkins
4. Darke RL, Vogl AW, Mitchell AWM, Tibbitts RM, Richardson PE (Çeviri ed. Prof. Dr. Sezgin İlgi, Prof. Dr. Mehmet Yıldırım. Gray?s Anatomi Atlası. (2009) Güneş Tıp Kitapevleri Ankara

PHYSIOLOGY
1. Berne RM, Levy MN, Koeppen BM, Staton AB.(2008) Fizyoloji 5.Baskı Çeviri: Türk Fizyolojik Bilimler Derneği. ÖncüBasımEvi.
2. Cooper GM (2000) The Cell: A MolecularApproach, 2nd Ed. SinauerAssociatesInc. Sunderland USA.
3. Costanzo, LS (2002) Physiology, Pennsylvania: Saunders, 2nd Ed.
4. Davies, A.,Blakeley, A.G.H., Kidd, C., (2001) Human Physiology, Churchill Livingstone, Spain, Harcourt Publishers Ltd.
5. Ganong, WF (2003) Review of Medical Physiology, USA:McGraw Hill,Twenty-first edition.
6. Guyton AC, Hall JE. (2007) Tıbbi Fizyoloji, 11. Baskı Çeviri: Çavuşoğlu H, Yeğen ÇB. YüceBasımve Nobel Tıp Kitabevi Ltd.
7. Gündoğan NÜ (2013) Uygulamalı Fizyoloji Laboratuvar Pratik Kitabı 2. Baskı, Başkent Üniversitesi Geliştirme Vakfı (BÜGEV) Yayınları, Ankara

HISTOLOGY AND EMBRIOLOGY
1. Kierszenbaum AL,Tres LL. (2012), Histology and Cell Biology: An Introduction to Pathology, Third Edition,Elsevier Saunders, Philadelphia.
2. Ross, Michael H. (2011). Histology A Textbook and Atlas. Sixth Edition, Williams and Wilkins, Philadelphia.
3. Gartner LP, Hiatt JL. (2007), Color Textbook of Histology, Third Edition, Saunders Elsevier, Philadelphia.
4. Fawcett, Don W. (1994). A Textbook of Histology. Twelfth Edition, Chapman and Hall, New York -London.
5. Moore KL, Persaud TVN, Torchia MG (2015). The Developing Human; Clinically Oriented Embryology, 10th Edition, Elsevier.

IMMUNOLOGY
1. Roitt I, Brotoff J, Male D. (2001) ?Immunology? Sixthedition, MosbyInc, Missouri USA.
2. Parslow TG, Stites DP, Terr AI, Imboden JB. (2001) ?MedicalImmunology? Tenthedition, McGraw-HillCompaniesinc., USA.
3. Abul K. Abbas, Andrew H. H. Lichtman, ShivPillai. (2014) Cellular andMolecularImmunology, 9th Edition. Elsevier.
4. Abul K. Abbas, Andrew H. H. Lichtman. (2007) Temelİmmünoloji Ed. YıldızCamcıoğlu, GünnurDeniz. İstanbulTıpKitapevi.
Additional Reference
1. http://www.med.sc.edu:85/book/welcome.html

MEDICAL BIOCHEMISTRY
1. Halliwell B, GutteridgeJMC,(2002), FreeRadicals in BiologyandMedicine. Third Edition, Oxford UniversityPress.
2. Devlin, TM, (2011), Textbook of BiochemistrywithClinicalCorrelations.,SixthEditions, Wiley-Liss.Inc., New York, USA.
3. Voet D, Voet JG, Pratt CW (2006), Fundamentals of Biochemistry. Second Edition, John WileyandSons, USA.
4. Baynes J, DominiczakMH,(1999), MedicalBiochemistry. Mosby, New York, USA.

MEDICAL GENETICS
1. Nussbaum RL, McInnes RR, Willard HF, Thompson MW (2016) Thompson&Thompsongenetics in medicine, 8th Edition. Philadelphia: Saunders/Elsevier.
2. Turnpenny P.,Ellard S., 2017 ?Emery'sElements of Medical Genetics? 15th edition, Churchill LıvıngstonElsevier.
3. Dündar M., 2016?Tıbbi GenetikveKlinikUygulamaları? Kayseri, MGRUP.
Planned Learning Activities and Teaching Methods
  • Report Preparation
  • Practice
  • Experiment
  • Problem Solving
  • Case Study
  • Questions/Answers
  • Discussion
  • Lecture
Assessment Methods and Criteria Summative Exam including Practical Exam (97%), Formative Exam (3%)
ECTS Allocated Based on Student Workload
Activities Quantity Duration (Hour) Total Workload (Hour)
Midterm exam
Preparation for Quiz
Individual or group work
Preparation for Final exam
Course hours
Preparation for Midterm exam
Laboratory (including preparation)
Final exam
Homework
Total Work Load0
Total Work Load / 30 (h)0
ECTS Credit of the Course4.5
Language of InstructionTurkish
Work Placement(s)No

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