Information Package
baskent.edu.tr

Ph.D. on Medical Genetics

GEN652

PROTEOMIC APPROACHES IN GENETICS

Course Code
GEN652
Semester
-
Theory+Practice
2 + 0
ECTS
10
Course TypeElective Course
Course LevelDoctorate Of Science
Year of Study-
Semester-
ECTS10
Name of Lecturer(s)
Learning Outcomes

At the end of this course, the students;

  1. Knows the concept of proteomics,
  2. Knows proteomic analysis methods
  3. Knows the basic concepts of interactome
  4. Knows proteomic approaches in health sciences
Mode of DeliveryFace to face
PrerequisitesNo
Recommended Optional Programme Components
Course DescriptionAt the end of the course, students are expected to understand proteomic concept, protein separation methods for proteomic analysis, 2-D polyacrylamide gel electrophoresis and spectrophotometric characterization of post-translational modifications, technologies for large-scale tandem mass spectrophotometry, structural proteomics with NMR, protein localization with cell visualization, yeast two hybrid systems, high output co-immunoprecipitation analysis, basic principles related to interactome and proteomic approaches in the field of healthcare.
Course Contents At the end of the course, students are expected to understand proteomic concept, protein separation methods for proteomic analysis, 2-D polyacrylamide gel electrophoresis and spectrophotometric characterization of post-translational modifications, technologies for large-scale tandem mass spectrophotometry, structural proteomics with NMR, protein localization with cell visualization, yeast two hybrid systems, high output co-immunoprecipitation analysis, basic principles related to interactome and proteomic approaches in the field of healthcare.
Recommended or Required Reading? Introduction to Proteomics: Principles and Applications. Nawin C. Mishra, Günter Blobel, (2010).
? Molecular Genetics and Personalized Medicine. D. Hunter Best ? Jeffrey J. Swensen Eds. Springer Science+Business Media, LLC (2012).
? Molecular Medicine ?Genomics to Personalized Healthcare?.4th ed. Ronald J Trent (2012).
Planned Learning Activities and Teaching Methods
  • Lecture
  • Discussion
  • Questions/Answers
  • Problem Solving
  • Experiment
  • Practice
  • Presentation
Assessment Methods and Criteria
Quantity Percentage (%)
Mid-term 1 30
Assignment 1 20
Total(%) 50
Contribution of In-term Studies to Overall Grade(%) 50
Contribution of Final Examination to Overall Grade(%) 50
Total(%) 100
ECTS Allocated Based on Student Workload
Activities Quantity Duration (Hour) Total Workload (Hour)
Midterm exam 1 2 2
Preparation for Quiz 2 3 6
Individual or group work 14 5 70
Preparation for Final exam 1 30 30
Course hours 14 3 42
Preparation for Midterm exam 1 20 20
Laboratory (including preparation)
Final exam 1 2 2
Homework 4 32 128
Total Work Load300
Total Work Load / 30 (h)10
ECTS Credit of the Course10
Language of InstructionTurkish
Work Placement(s)No

Programme Qualifications / Learning Outcomes

LO1 LO2 LO3 LO4
K1 X X X X
K2 X X X X
K3 X X
K4 X
K5
K6 X X X
K7 X X X
K8 X X X X
K9 X X X X