| Course Type | Elective Course |
|---|
| Course Level | Master's Degree With Thesis |
|---|
| Year of Study | - |
|---|
| Semester | - |
|---|
| ECTS | 6 |
|---|
| Name of Lecturer(s) |
|
| Learning Outcomes |
At the end of this course, the students;
- Knows the concepts of genetic changes, polymorphisms, and mutations,
- Knows chromosomal and sequence changes in the genome structure,
- Knows the classiffication of mutations according to functions and their phenotypic effects,
- Knows physical and chemical mutagens,
- Knows proofreading and repair mechanisms to protect genetic integrity in cells,
- Knows somatic and germline mutations,
- Knows the role of mutations in pathogenesis of diseases
|
| Mode of Delivery | Face to face |
|---|
| Prerequisites | No |
|---|
| Recommended Optional Programme Components | None |
|---|
| Course Description | The concepts of genetic changes, polymorphisms, and mutations, chromosomal and sequence changes in the genome structure, classiffications according to functions and their phenotypic effects, molecular mechanisms of mutations, physical and chemical mutagens, proofreading and repair mechanisms to protect genetic integrity in cells, somatic and germline mutations, role of mutations in pathogenesis of diseases will be explained in the course. |
|---|
| Course Contents |
| WEEK |
TOPICS |
|
1st Week |
The concepts of genetic changes, polymorphisms, and mutations, |
|
2nd Week |
Chromosomal and sequence changes in the genome structure, |
|
3rd Week |
The classiffication of mutations according to functions and their phenotypic effects, |
|
4th Week |
Molecular mechanisms of mutations, |
|
5th Week |
Physical and chemical mutagens, |
|
6th Week |
Proofreading and repair mechanisms to protect genetic integrity in cells, |
|
7th Week |
Somatic and germline mutations, |
|
8th Week |
The role of mutations in pathogenesis of diseases |
|
9th Week |
|
|
| Recommended or Required Reading | Molecular Biology of the Gene (7th Edition). James D. Watson, Tania A. Baker, Stephen P. Bell, Alexander Gann, Michael Levine. Benjamin Cummings Press, 2013. |
|---|
| Planned Learning Activities and Teaching Methods |
- Lecture
- Discussion
- Questions/Answers
- Presentation
|
|---|
| Assessment Methods and Criteria |
|
Quantity |
Percentage (%) |
| Mid-term |
1 |
30 |
| Assignment |
1 |
20 |
| Total(%) |
|
50 |
| Contribution of In-term Studies to Overall Grade(%) |
|
50 |
| Contribution of Final Examination to Overall Grade(%) |
|
50 |
| Total(%) |
|
100 |
|
| ECTS Allocated Based on Student Workload |
| Activities |
Quantity |
Duration (Hour) |
Total Workload (Hour) |
| Midterm exam |
1 |
2 |
2 |
| Preparation for Quiz |
1 |
5 |
5 |
| Individual or group work |
14 |
2 |
28 |
| Preparation for Final exam |
1 |
20 |
20 |
| Course hours |
14 |
3 |
42 |
| Preparation for Midterm exam |
1 |
11 |
11 |
| Laboratory (including preparation) |
|
|
|
| Final exam |
1 |
2 |
2 |
| Homework |
2 |
35 |
70 |
| Total Work Load | 180 |
| Total Work Load / 30 (h) | 6 |
| ECTS Credit of the Course | 6 |
|
| Language of Instruction | Turkish |
|---|
| Work Placement(s) | No |
|---|
