MOLECULAR BIOTECHNOLOGY FOR ENGINEERS

BME620

Course Code: BME620
Semester: -
Theory+Practice: 3 + 0
ECTS: 10

Course Type

Elective Course

Course Level

Doctorate Of Science

Year of Study

Semester

ECTS

Name of Lecturer(s)

Professor Özlem Darcansoy İşeri

Learning Outcomes

At the end of this course, the students;

To have knowledge on biotechnological products, process concepts and principles
To understand the basic principles and applications of genetic manipulation in biotechnology
To have knowledge on different cell types and their products
To understand omic technologies and their applications
To understand basic principles of bioremediation and biomass utilization
To discuss current applications of molecular biotechnology in social, ethical and legal perspectives

Mode of Delivery

Face to face

Prerequisites

Recommended Optional Programme Components

None

Course Description

Biotechnology Market and Biotechnological Products; Basic Principles of Biotechnological Processes Bioreactors and Principles of Cellular Production; Biomolecular Principles from Gene to Protein Basic Principles of Molecular Cloning and Gene Engineering; Recombinant DNA Technology and Heterologous Protein Production Gene Delivery into Cells and Transgenic Organisms; Protein Engineering and Protein Therapeutics Hybridoma Technology and Monoclonal Antibody Production; Omic Technologies; Bioremediation and Biomass Utilization Society, Ethics and Legal Regulations

Course Contents

WEEK	TOPICS
1^st Week	Biotechnology Market and Biotechnological Products
2^nd Week	Process Principles in Biotechnology
3^rd Week	Bioreactors and Principles of Cellular Production
4^th Week	Biomolecular Principles from Gene to Protein
5^th Week	Molecular Cloning and Basic Principles of Genetic Engineering
6^th Week	Recombinant DNA Technology and Heterologous Protein Production
7^th Week	Gene Transfer to Cells and Transgenic Organisms
8^th Week	Midterm Week
9^th Week	Protein Engineering and Protein Therapeutics
10^th Week	Hybridoma Technology and Monoclonal Antibody Production
11^th Week	Omic Technologies
12^th Week	Bioremediation and Biomass Utilization
13^th Week	Social, Ethical and Legal Issues
14^th Week	Presentations

Recommended or Required Reading

Introduction to Biotechnology (3rd Edition). William J. Thieman, Michael A. Palladino, Benjamin Cummings Press, 2012.
Molecular Biotechnology, Principles and Applications of Recombinant DNA. Bernard R. Glick, Jack J. Pasternak, ASM Press, Washington, D.C., 2009.
Principles of Gene Manipulation and Genomics, 7th Edition, Sandy B. Primrose, Richard Twyman, Wiley-Blackwell, 2006.
Internet and library files.

Planned Learning Activities and Teaching Methods

Lecture
Discussion
Presentation

Assessment Methods and Criteria

	Quantity	Percentage (%)
Mid-term	1	35
Assignment	1	15
Total(%)		50
Contribution of In-term Studies to Overall Grade(%)		50
Contribution of Final Examination to Overall Grade(%)		50
Total(%)		100

ECTS Allocated Based on Student Workload

Activities	Quantity	Duration (Hour)	Total Workload (Hour)
Midterm exam	1	72	72
Preparation for Quiz	0	0	0
Individual or group work	2	3	6
Preparation for Final exam	1	24	24
Course hours	14	3	42
Preparation for Midterm exam	1	24	24
Laboratory (including preparation)	0	0	0
Final exam	1	96	96
Homework	1	24	24
Total Work Load			288
Total Work Load / 30 (h)			9.6
ECTS Credit of the Course			10

Language of Instruction

English

Work Placement(s)

Programme Qualifications / Learning Outcomes

	LO1	LO2	LO3	LO4	LO5	LO6
K1	X	X	X	X	X	X
K2
K3						X
K4	X	X	X	X	X
K5
K6						X
K7
K8						X