PHARMACOLOGY OF CENTRAL NERVOUS SYSTEM

PHAR646

Course Code: PHAR646
Semester: -
Theory+Practice: 2 + 0
ECTS: 5

Course Type

Elective Course

Course Level

Doctorate Of Science

Year of Study

Semester

ECTS

Name of Lecturer(s)

Learning Outcomes

At the end of this course, the students;

explain the anathomicophysiology of the central nervous system (CNS)
to classify the drugs acting on central nervous system
to describe the effects, mechanisms of action, adverse reactions, contraindications and clinical uses of drugs acting on the central nervous system

Mode of Delivery

Face to face

Prerequisites

Recommended Optional Programme Components

Course Description

An elective course to accomplish a comprehensive understanding of the functional anatomophysiology of the central nervous system, main mechanisms of the interactions between the central nervous system system and drugs

Course Contents

WEEK	TOPICS
1^st Week	1) Basic anatomy, physiology and neurotransmitters of central nervous system
2^nd Week	2) Neurotransmission, synapse and synaptic transmission
3^rd Week	3) Pharmacology of general and local anesthetics
4^th Week	4) Neuromuscular blocking agents and their clinical pharmacology
5^th Week	5) Centrally acting myorelaxants
6^th Week	6) Hypnosedative drugs and their clinical pharmacology
7^th Week	7) Antipsychotic drugs and their clinical pharmacology
8^th Week	8) Opioid analgesics and their clinical pharmacology
9^th Week	9) Drugs used fort he treatment of neurodegenerative disorders
10^th Week	10) Drug/subtance dependence, addiction
11^th Week	11) Central nervous sytem stimulants
12^th Week	12) Antiseizure drugs and their clinical pharmacology

Recommended or Required Reading

1. Goodman and Gilman?s The Pharmacological Basis of Therapeutics, Brunton LL, Hilal-Dandan R, Knollmann BC (Ed.s), 13th edition, McGraw Hill, 2018, USA, ISBN 978-1-25-958473-2.
2. Basic and Clinical Pharmacology, Katzung BG, (Ed.), 14th ediition, McGraw Hill, 2018, USA, ISBN 978-1-259-64115-2.
3. Rang and Dale?s Pharmacology, Ritter JM, Flower R, Henderson G, Loke YK, MacEwan D, Rang HP (Ed.s), 9th edition, Elsevier, 2020, UK, ISBN 978-0-7020-7448-6.
4. Receptor-Ligand Interactions: A Practical Approach, Hulme E.C. (Ed.), Oxfoed University Press, NY, USA, 1992.
5. Netter?s Illustrated Pharmacology, R.B. Baffa, Rawls S.M., Beyzarov E.P. (Ed.s), Icon Learning Systems, A.B.D., 2005.
6. Akılcıl Tedavi Yönünden Tıbbi Farmakoloji, Prof. Dr. S. Oğuz Kayaalp (Ed.), 13. baskı, Pelikan Yay. Ltd. Şti., Ankara, Türkiye, 2012 (ISBN: 978-605-5270-10-0).
7. Goodman ve Gilman?ın Farmakoloji ve Tedavi El Kitabı, Hilal-Dandan R., Brunton L.L. (Ed.s), Erdem Ş.R. (Tr. Ed.), 2. Baskı, McGraw Hill, Güneş Tıp Kitabevleri, Ankara, Türkiye, 2017, ISBN978-0-07-179288-2

Planned Learning Activities and Teaching Methods

Lecture
Discussion
Questions/Answers
Problem Solving

Assessment Methods and Criteria

Formative: Mid-term exams and homeworks Summative: Final exam and homeworks

ECTS Allocated Based on Student Workload

Activities	Quantity	Duration (Hour)	Total Workload (Hour)
Midterm exam	1	2	2
Preparation for Quiz	4	3	12
Individual or group work	14	4	56
Preparation for Final exam	1	14	14
Course hours	14	2	28
Preparation for Midterm exam	1	14	14
Laboratory (including preparation)	0	0	0
Final exam	1	3	3
Homework	7	3	21
Total Work Load			150
Total Work Load / 30 (h)			5
ECTS Credit of the Course			5

Language of Instruction

Turkish

Work Placement(s)

Programme Qualifications / Learning Outcomes

	LO1	LO2	LO3
K1	X	X	X
K2
K3
K4
K5
K6
K7
K8	X	X	X
K9