Information Package

Ph.D. on Pharmacology

PHAR645

PHARMACOLOGY OF CARDIOVASCULAR SYSTEM

Course Code
PHAR645
Semester
-
Theory+Practice
2 + 0
ECTS
5
Course TypeElective Course
Course LevelDoctorate Of Science
Year of Study-
Semester-
ECTS5
Name of Lecturer(s) -
Learning Outcomes

At the end of this course, the students;

  1. conduct selected neuropsychopharmacologic, molecular, electrophysiologic experiments
  2. use the physiological data acquisition systems, image processing systems, analyze behavioral data
  3. record and analyze the findings he/she obtained, alone
Mode of DeliveryFace to face
PrerequisitesNo
Recommended Optional Programme Components
Course DescriptionA mandatory practical course to help the student achieve the ability of making experiments on neuropsychopharmacological models in vivo, using electrophysiological equipment and molecular pharmacology setups, and of obtaining reliable, reproducible experimental data and of of analyzing them
Course Contents
WEEK TOPICS
1st Week 1) Basic principles in neuropsychopharmacological experiments
2nd Week 2) Experimental stress models
3rd Week 3) Experimental models for spatial learning-memory performance evaluation
4th Week 4) Experimental models for prefrontal cortex-related learning-memory performance evaluation
5th Week 5) Experimental models for evaluating the anxiety status
6th Week 6) Experimental models for evaluating depression-like behaviors
7th Week 7) Experimental models for evaluating risk assessment performance
8th Week 8) Experimental models for evaluation locomotor aktkivity
9th Week 9) Experimental models for substance/drug addiction
10th Week 10) Experimental models of schysophrenia
11th Week 11) Basic principles of elektrophysiology, and selected electrophysiological experiments
12th Week 12) Basic principles of molecular pharmacology, and selected molecular pharmacology experiments
Recommended or Required Reading1) Experimental Therapeutics, Wilkins M.R. (Ed.), Taylor&Francis, Londra, UK, 2003, ISBN 1-84184-290-7
2) Laboratory Animal Anesthesia, Flecknell P.A. (Ed.), 1987, Academic Press, San Diego, CA, USA, ISBN 0-12-260360-5
3) Nerve and Muscle, Keynes R.D, Aidley D.J. (Ed.s), 2nd edition, 1995, Cambridge University Press, USA, ISBN 0 521 42255 8
4) Hücre elektrofizyolojisi ve görüntülemenin temelleri, N. Puralı, Veri Yayıncılık, 2009
5) Psikofarmakolojinin temelleri ve deneysel araştırma teknikleri, T. Uzbay, Çizgi Tıp Yayınevi, Ankara, 2004.
6) Molecular Pharmacology: A Short Course, Kenakin T.,Blackwell Science, USA, 1997, ISBN 0-86542-540-X
7) Sinir, Kas ve Sinaps: Elektrofizyolojiye Giriş, Katz B., Küçükhüseyin C. (Tr. Ed.), İ.Ü. Basımevi, İstanbul, Türkiye,1992, ISBN 975-404-321-3
8) Deneysel Farmakoloji, Kaymakçalan Ş., Türker K., Ankara Üniversitesi yayınları, no 142, 1964, Ankara, Türkiye
9) Goodman and Gilman?s The Pharmacological Basis of Therapeutics, Brunton LL, Hilal-Dandan R, Knollmann BC (Ed.s), 13th edition, McGraw Hill, 2018, USA, ISBN 978-1-25-958473-2.
10) Basic and Clinical Pharmacology, Katzung BG, (Ed.), 14th ediition, McGraw Hill, 2018, USA, ISBN 978-1-259-64115-2.
11) Rang and Dale?s Pharmacology, Ritter JM, Flower R, Henderson G, Loke YK, MacEwan D, Rang HP (Ed.s), 9th edition, Elsevier, 2020, UK, ISBN 978-0-7020-7448-6.
12) Akılcıl Tedavi Yönünden Tıbbi Farmakoloji, Prof. Dr. S. Oğuz Kayaalp (Ed.), 13. baskı, Pelikan Yay. Ltd. Şti., Ankara, Türkiye, 2012 (ISBN: 978-605-5270-10-0).
13) Goodman ve Gilman?ın Farmakoloji ve Tedavi El Kitabı, Hilal-Dandan R., Brunton L.L. (Ed.s), Erdem Ş.R. (Tr. Ed.), 2. Baskı, McGraw Hill, Güneş Tıp Kitabevleri, Ankara, Türkiye, 2017, ISBN978-0-07-179288-2
Planned Learning Activities and Teaching Methods
  • Uygulamalı
  • yüz yüze
  • nöropsikofarmakoloji
  • elektrofizyoloji
  • moleküler farmakoloji deneyler i
  • Problem Solving
  • Experiment
  • Practice
Assessment Methods and Criteria Formative: Homeworks and midterm exam Summative: Task-based final exam and experiment report Course grade is calculated by addition of 75% of the mark received for the task-based final exam report, and 25% of the average marks received for the performance during the course, midterm exam and homeworks
ECTS Allocated Based on Student Workload
Activities Quantity Duration (Hour) Total Workload (Hour)
Midterm exam 1 2 2
Preparation for Quiz 4 3 12
Individual or group work 14 4 56
Preparation for Final exam 1 14 14
Course hours 14 2 28
Preparation for Midterm exam 1 14 14
Laboratory (including preparation) 0 0 0
Final exam 1 3 3
Homework 7 3 21
Total Work Load150
Total Work Load / 30 (h)5
ECTS Credit of the Course5
Language of InstructionTurkish
Work Placement(s)No
LO1 LO2 LO3
K1 X X X
K2
K3
K4
K5
K6 X X X
K7
K8 X X X
K9