FUNCTIONAL ANATOMY, PHARMACOLOGY AND SIGNALING IN THE CELL

PHAR639

Course Code: PHAR639
Semester: -
Theory+Practice: 2 + 0
ECTS: 5

Course Type

Elective Course

Course Level

Doctorate Of Science

Year of Study

Semester

ECTS

Name of Lecturer(s)

Learning Outcomes

At the end of this course, the students;

Tell the anatomic and functional features/properties of the cell in detail
Explain the cellular mechanisms mediating drugs? effects in detail

Mode of Delivery

Face to face

Prerequisites

Recommended Optional Programme Components

Course Description

An elective course to help the student understand the relationship between the functional anatomy of the cell and cellular mechanisms mediating the effects of drugs

Course Contents

WEEK	TOPICS
1^st Week	1) Cell membrane structure
2^nd Week	2) Organelles: Nucleus, Endoplasmic Reticulum and Golgi apparatus, Lysosom, Mithochondria, Peroxysom
3^rd Week	3) Intracellular skeleton proteins
4^th Week	4) Extracellular matrix
5^th Week	5) Molecules mediating drug effects
6^th Week	6) Receptors, receptor types
7^th Week	7) Secondary messengers
8^th Week	8) Ion channels
9^th Week	9) Enzymes
10^th Week	10) Carrier molecules

Recommended or Required Reading

1. Goodman and Gilman?s The Pharmacological Basis of Therapeutics, Brunton LL, Hilal-Dandan R, Knollmann BC (Ed.s), 13th edition, McGraw Hill, 2018, USA, ISBN 978-1-25-958473-2
2. Basic and Clinical Pharmacology, Katzung BG, (Ed.), 14th ediition, McGraw Hill, 2018, USA, ISBN 978-1-259-64115-2
3. Rang and Dale?s Pharmacology, Ritter JM, Flower R, Henderson G, Loke YK, MacEwan D, Rang HP (Ed.s), 9th edition, Elsevier, 2020, UK, ISBN 978-0-7020-7448-6
4. Molecular Biology of the Cell, B. Alberts, A. Johnson, J. Lewis, D. Morgan, M. Raff, K. Roberts, P. Walter (Ed.ler), sixth edition, Garland Science, 2015, USA, ISBN 978-0-8153-4464-3
5. Molecular Pharmacology: A Short Course, Kenakin T (Ed.), Blackwell Science, 1997, USA, ISBN 0-86542-540-X

Planned Learning Activities and Teaching Methods

Kuramsal
interaktif
yüz yüze tartışmalar
ödevler Lecture
Discussion
Questions/Answers
Problem Solving

Assessment Methods and Criteria

Formative: midterm exam, homeworks, performance Summative: final exam Course grade is determined by adding 25% of the midterm exam grade, 65% of final exam grade, and 10% of the mark given upon evaluation of course performance and homeworks

ECTS Allocated Based on Student Workload

Activities	Quantity	Duration (Hour)	Total Workload (Hour)
Midterm exam	1	2	2
Preparation for Quiz	4	3	12
Individual or group work	14	4	56
Preparation for Final exam	1	14	14
Course hours	14	2	28
Preparation for Midterm exam	1	14	14
Laboratory (including preparation)	0	0	0
Final exam	1	3	3
Homework	7	3	21
Total Work Load			150
Total Work Load / 30 (h)			5
ECTS Credit of the Course			5

Language of Instruction

Turkish

Work Placement(s)

Programme Qualifications / Learning Outcomes

	LO1	LO2
K1	X	X
K2
K3
K4
K5
K6	X	X
K7
K8	X	X
K9