Information Package
baskent.edu.tr

Ph.D. on Pharmacology

PHAR633

PHARMACOKINETICS

Course Code
PHAR633
Semester
First Term (Fall)
Theory+Practice
2 + 0
ECTS
5
Course TypeCompulsory Course
Course LevelDoctorate Of Science
Year of Study1
SemesterFirst Term (Fall)
ECTS5
Name of Lecturer(s) -
Learning Outcomes

At the end of this course, the students;

  1. explain the pharmacokinetic processes (absorption, distribution, biotransformation, elimination) in detail
  2. discuss the importance of pharmacokinetics in clinical practice
Mode of DeliveryFace to face
PrerequisitesNo
Recommended Optional Programme Components
Course DescriptionA mandatory course to help the student comprehend the importance and principles of pharmacokinetic properties of drugs
Course Contents
WEEK TOPICS
1st Week 1) Dissolution, absorption and related processes
2nd Week 2) Routes and linetic properties of of drug administration
3rd Week 3) Bioavailability, its evaluation and measurement,
4th Week 4) Bioequivalence, its evaluation and legislative issues regarding bioequivalence
5th Week 5) Drug distribution and its kinetics
6th Week 6) Drug metabolism and drug-enzyme interaction
7th Week 7) Elimination of drugs, kinetic perpectives, dose- and time-dependency of elimination
8th Week 8) Dose-/concentration-response relationship and variability in drug response
9th Week 9) Pharmacogenetics
10th Week 10) Pharmacokinetic interactions
Recommended or Required Reading1. Goodman and Gilman?s The Pharmacological Basis of Therapeutics, Brunton LL, Hilal-Dandan R, Knollmann BC (Ed.s), 13th edition, McGraw Hill, 2018, USA, ISBN 978-1-25-958473-2.
2. Basic and Clinical Pharmacology, Katzung BG, (Ed.), 14th ediition, McGraw Hill, 2018, USA, ISBN 978-1-259-64115-2.
3. Rang and Dale?s Pharmacology, Ritter JM, Flower R, Henderson G, Loke YK, MacEwan D, Rang HP (Ed.s), 9th edition, Elsevier, 2020, UK, ISBN 978-0-7020-7448-6.
4. Clinical Pharmacokinetics, Rowland M., Tozer T.N. (Ed.s), 3rd edition, 1995, Manchester, UK.
5. Klinik ve Uygulamalı Farmakokinetik (Pharmacokinetics: Applied and Clinical Perspectives), Hatip İ. 1. Baskı, 2004, Nobel Tıp Kitabevleri, İstanbul, Türkiye.
6. Netter?s Illustrated Pharmacology, R.B. Baffa, Rawls S.M., Beyzarov E.P. (Ed.s), Icon Learning Systems, A.B.D., 2005.
7. Akılcıl Tedavi Yönünden Tıbbi Farmakoloji, Prof. Dr. S. Oğuz Kayaalp (Ed.), 13. baskı, Pelikan Yay. Ltd. Şti., Ankara, Türkiye, 2012 (ISBN: 978-605-5270-10-0).
8. Goodman ve Gilman?ın Farmakoloji ve Tedavi El Kitabı, Hilal-Dandan R., Brunton L.L. (Ed.s), Erdem Ş.R. (Tr. Ed.), 2. Baskı, McGraw Hill, Güneş Tıp Kitabevleri, Ankara, Türkiye, 2017, ISBN978-0-07-179288-2
Planned Learning Activities and Teaching Methods Kanıta dayalı tıp anlayışıyla yürütülecek kuramsal, interaktif, yüzyüze dersler ve tartışmalar, Lecture, Discussion, Questions/Answers, Problem Solving
Assessment Methods and Criteria Formative: Mid-term exams and homeworks Summative: Final exam and homeworks
ECTS Allocated Based on Student Workload
Activities Quantity Duration (Hour) Total Workload (Hour)
Midterm exam 1 2 2
Preparation for Quiz 4 3 12
Individual or group work 14 4 56
Preparation for Final exam 1 14 14
Course hours 14 2 28
Preparation for Midterm exam 1 14 14
Laboratory (including preparation) 0 0 0
Final exam 1 3 3
Homework 7 3 21
Total Work Load150
Total Work Load / 30 (h)5
ECTS Credit of the Course5
Language of InstructionTurkish
Work Placement(s)No

Programme Qualifications / Learning Outcomes

LO1 LO2
K1 X X
K2
K3
K4
K5
K6
K7
K8 X X
K9