Information Package
baskent.edu.tr

Ph.D. on Pharmacology

PHAR608

MECHANISMS OF DRUG ACTION

Course Code
PHAR608
Semester
First Term (Fall)
Theory+Practice
2 + 0
ECTS
5
Course TypeCompulsory Course
Course LevelDoctorate Of Science
Year of Study1
SemesterFirst Term (Fall)
ECTS5
Name of Lecturer(s) -
Learning Outcomes

At the end of this course, the students;

  1. Tell the mechanisms of drug action
  2. Describe each mechanism in detail
  3. Explain the related concepts
  4. Discuss its importance in clinical practice
Mode of DeliveryFace to face 50% + E-Learning 50%
PrerequisitesNo
Recommended Optional Programme Components
Course DescriptionA course to help the student comprehend the main mechanisms of action of drugs
Course Contents
WEEK TOPICS
1st Week -Comprehension of the mechanisms of action of drugs in detail by the help of current scientfic knowledge
2nd Week -Specifity of drug response, structure-activity relatonship, drug design
3rd Week -Receptor, acceptor concepts
4th Week -Quantitative measures of drug-receptor interaction
5th Week -Receptors affecting the concentrations of endogenous ligands
6th Week -Receptors regulating the ionic environment
7th Week -Cellular pathway activated by physiological receptors
8th Week -Structural and functional receptor families
9th Week -G protein-coupled receptros, secondary messenger systems
10th Week -Ion channels
11th Week -Transmembrane receptors associated with intracellular enzymes
12th Week -Nuclear hormone receptors and transcription factors
13th Week -Physiological systems integrating multiple systems
Recommended or Required Reading1. Goodman and Gilman?s The Pharmacological Basis of Therapeutics, Brunton LL, Hilal-Dandan R, Knollmann BC (Ed.s), 13th edition, McGraw Hill, 2018, USA, ISBN 978-1-25-958473-2
2. Basic and Clinical Pharmacology, Katzung BG, (Ed.), 14th ediition, McGraw Hill, 2018, USA ISBN 978-1-259-64115-2
3. Rang and Dale?s Pharmacology, Ritter JM, Flower R, Henderson G, Loke YK, MacEwan D, Rang HP (Ed.s), 9th edition, Elsevier, 2020, UK, ISBN 978-0-7020-7448-6
4. Pharmacology, G.M. Brenner ve C. W. Stevens (editörler), üçüncü baskı, Saunders Elsevier, Philadelphia, A.B.D., 2010.
5. Drug Interactions Handbook, K.A. Bachman (editör), Lexi-Comp Inc., Hudson-Ohio, 2003.
6. BNF/TİK-6 Türkiye İlaçla Tedavi Kılavuzu-2011-12 Formüleri, S.Oğuz Kayaalp (ed.), Pelikan Yay. Ltd. Şti., Ankara, 2011 (ISBN: 978-605-5529-49-9).
7. Netter?s Illustrated Pharmacology, R.B. Baffa, Rawls S.M., Beyzarov E.P. (editörler), Icon Learning Systems, A.B.D., 2005.
8. Akılcıl Tedavi Yönünden Tıbbi Farmakoloji, Prof. Dr. S. Oğuz Kayaalp (ed.), 13. baskı, Pelikan Yay. Ltd. Şti., Ankara, 2012 (ISBN: 978-605-5270-10-0).
Planned Learning Activities and Teaching Methods Kanıta dayalı tıp anlayışıyla yürütülecek kuramsal, interaktif, yüzyüze dersler ve tartışmalar, Lecture, Discussion, Questions/Answers, Problem Solving
Assessment Methods and Criteria Formative: Mid-term exams and homeworks Summative: Final exam and homeworks
ECTS Allocated Based on Student Workload
Activities Quantity Duration (Hour) Total Workload (Hour)
Midterm exam 1 2 2
Preparation for Quiz 4 3 12
Individual or group work 14 4 56
Preparation for Final exam 1 14 14
Course hours 14 2 28
Preparation for Midterm exam 1 14 14
Laboratory (including preparation) 0 0 0
Final exam 1 3 3
Homework 7 3 21
Total Work Load150
Total Work Load / 30 (h)5
ECTS Credit of the Course5
Language of InstructionEnglish
Work Placement(s)No

Programme Qualifications / Learning Outcomes

LO1 LO2 LO3 LO4
K1 X X X X
K2 X
K3
K4
K5
K6
K7
K8 X X X X
K9